Immune fluorescence of HIP cardiomyocytes in a dish; Photo courtesy of UCSF Transplanting cells or an entire organ from one person to another can be lifesaving but it comes with a cost. To avoid the recipient’s body rejecting the cells or organ the patient has to be given powerful immunosuppressive medications. Those medications weaken the … Continue reading A new way to evade immune rejection in transplanting cells
iPSCs
Friday Round Up
Here’s a look at a couple of stories that caught our eye this week: Jasper Therapeutics has had a busy couple of weeks. Recently they announced data from their Phase 1 clinical trial treating people with Myelodysplastic syndromes (MDS). This is a group of disorders in which immature blood-forming cells in the bone marrow become … Continue reading Friday Round Up
CIRM funded study uses drug development in a dish for treatment of heart arrhythmias
Image Credit: Center for Disease Control and Prevention (CDC) Cardiac (heart) arrhythmias occur when electrical impulses that coordinate your heartbeats don't work properly, causing your heart to beat too fast, too slow, or in an irregular manner. In the U.S. alone, almost one million individuals are hospitalized every year for heart arrhythmias. Close to 300,000 … Continue reading CIRM funded study uses drug development in a dish for treatment of heart arrhythmias
CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Dr. Yanhong Shi (left) and Dr. Vaithilingaraja Arumugaswami (right) All this month we are using our blog and social media to highlight a new chapter in CIRM’s life, thanks to the voters approving Proposition 14. We are looking back at what we have done since we were created in 2004, and also looking forward to the … Continue reading CIRM funded researchers discover link between Alzheimer’s gene and COVID-19
Stem cell research reveals path to schizophrenia
3d illustration of brain nerve cells - Photo courtesy Science Photo If you don’t know what’s causing a problem it’s hard to come up with a good way to fix it. Mental health is the perfect example. With a physical illness you can see what the problem is, through blood tests or x-rays, and develop … Continue reading Stem cell research reveals path to schizophrenia
Persistence pays off in search for clue to heart defects
A team of scientists led by Benoit Bruneau (left), including Irfan Kathiriya (center) and Kavitha Rao (right), make inroads into understanding what genes are improperly deployed in some cases of congenital heart disease. Photo courtesy Gladstone Institute For more than 20 years Dr. Benoit Bruneau has been trying to identify the causes of congenital heart … Continue reading Persistence pays off in search for clue to heart defects
You can’t take it if you don’t make it
Biomedical specialist Mamadou Dialio at work in the Cedars-Sinai Biomanufacturing Center. Photo by Cedars-Sinai. Following the race to develop a vaccine for COVID-19 has been a crash course in learning how complicated creating a new therapy is. It’s not just the science involved, but the logistics. Coming up with a vaccine that is both safe … Continue reading You can’t take it if you don’t make it
Precision guided therapy from a patient’s own cells
Dr. Wesley McKeithan, Stanford Imagine having a tool you could use to quickly test lots of different drugs against a disease to see which one works best. That’s been a goal of stem cell researchers for many years but turning that idea into a reality hasn’t been easy. That may be about to change. A … Continue reading Precision guided therapy from a patient’s own cells
Therapy developed with CIRM award used in new clinical trial for COVID-19
Dr. Joshua Rhein, Assistant Professor of Medicine in the University of Minnesota Medical School's Division of Infectious Diseases and International Medicine Image Credit: University of Minnesota While doctors are still trying to better understand how to treat some of the most severe cases of COVID-19, researchers are looking at their current scientific "toolkit" to see if … Continue reading Therapy developed with CIRM award used in new clinical trial for COVID-19
Stem cells used to promote quick and precise bone healing
A close-up view of the intricate microarchitecture of the pluripotent stem-cell-derived extracellular matrix. Image Credit: Carl Gregory/Texas A&M Although some broken bones can be mended with the help of a cast, others require more complex treatments. Bone grafts, which can come from the patient's own body or a donor, are used to transplant bone tissue … Continue reading Stem cells used to promote quick and precise bone healing
The Stem Cellar 