One of the great pleasures of my job is getting to meet the high school students who take part in our SPARK or Summer Internship to Accelerate Regenerative Medicine Knowledge program. It's a summer internship for high school students where they get to spend a couple of months working in a world class stem cell … Continue reading The present and future of regenerative medicine
heart attack
Using stem cells and smart machines to warn of heart problems
Despite advances in treatments in recent years heart disease remains the leading cause of death in the US. It accounts for one in three deaths in this country, and many people are not even aware they have a problem until they have a heart attack. One of the early warning signs of danger is a … Continue reading Using stem cells and smart machines to warn of heart problems
CIRM funds clinical trials targeting heart disease, stroke and childhood brain tumors
Gary Steinberg (Jonathan Sprague) Heart disease and stroke are two of the leading causes of death and disability and for people who have experienced either their treatment options are very limited. Current therapies focus on dealing with the immediate impact of the attack, but there is nothing to deal with the longer-term impact. The CIRM … Continue reading CIRM funds clinical trials targeting heart disease, stroke and childhood brain tumors
A new way to evade immune rejection in transplanting cells
Immune fluorescence of HIP cardiomyocytes in a dish; Photo courtesy of UCSF Transplanting cells or an entire organ from one person to another can be lifesaving but it comes with a cost. To avoid the recipient’s body rejecting the cells or organ the patient has to be given powerful immunosuppressive medications. Those medications weaken the … Continue reading A new way to evade immune rejection in transplanting cells
Two voices, one message, watch out for predatory stem cell clinics
Last week two new papers came out echoing each other about the dangers of bogus “therapies” being offered by predatory stem cell clinics and the risks they pose to patients. The first was from the Pew Charitable Trusts entitled: ‘Harms Linked to Unapproved Stem Cell Interventions Highlight Need for Greater FDA Enforcement’ with a subtitle: … Continue reading Two voices, one message, watch out for predatory stem cell clinics
Scientists at UC Davis discover a way to help stem cells repair heart tissue
Researchers Phung Thai (left) and Padmini Sirish were part of a research team seeking stem cell solutions to heart failure care. Image Credit: UC Davis Repairing the permanent damage associated with a heart attack or long-term heart disease has been a challenge that scientists have been trying to tackle for a long time. Heart failure … Continue reading Scientists at UC Davis discover a way to help stem cells repair heart tissue
Creating a platform to help transplanted stem cells survive after a heart attack
Repairing, even reversing, the damage caused by a heart attack is the Holy Grail of stem cell researchers. For years the Grail seemed out of reach because the cells that researchers transplanted into heart attack patients didn’t stick around long enough to do much good. Now researchers at Stanford may have found a way around … Continue reading Creating a platform to help transplanted stem cells survive after a heart attack
How mice and zebrafish are unlocking clues to repairing damaged hearts
Researchers at the University of Southern California identified a gene that may help regenerate damaged heart tissue after a heart attack. in the journal Nature Genetics. Declining Regenerative Heart Cells with AgeAt birth, we have many mononuclear diploid cardiomyocytes (MNDCMs), heart muscle cells with strong regenerative power. As we age, MNDCM levels drop sharply. By … Continue reading How mice and zebrafish are unlocking clues to repairing damaged hearts
Using skin cells to repair damaged hearts
When someone has a heart attack, getting treatment quickly can mean the difference between life and death. Every minute delay in getting help means more heart cells die, and that can have profound consequences. One study found that heart attack patients who underwent surgery to re-open blocked arteries within 60 minutes of arriving in the … Continue reading Using skin cells to repair damaged hearts
UCLA Study Suggests New Way to Mend a Broken Heart
When you suffer a heart attack, your heart-muscle cells become deprived of oxygen. Without oxygen, the cells soon whither and die—and are entombed within scar tissue. And once these cells die, they can’t be brought back to life. But maybe—just maybe—there is another way to build new heart muscle. And if there is, scientists like … Continue reading UCLA Study Suggests New Way to Mend a Broken Heart