The governing Board of the California Institute for Regenerative Medicine (CIRM) has awarded almost $12 million to carry out a clinical trial targeting brain tumors. This brings the total number of CIRM funded clinical trials to 83. $11,999,984 was awarded to Dr. Jana Portnow at the Beckman Research Institute of City of Hope. They are using Neural stem … Continue reading CIRM Board Approves Funding for New Clinical Trial Targeting Brain Tumors
glioblastoma
City of Hope researchers discover potential therapy to treat brain tumors
Glioblastoma (GBM) is a common type of aggressive brain tumor that is found in adults. Survival of this type of brain cancer is poor with just 40% survival in the first-year post diagnosis and 17% in the second year, according to the American Association of Neurological Surgeons. This disease has taken the life of former … Continue reading City of Hope researchers discover potential therapy to treat brain tumors
Latest CIRM TRAN1 awards focus on CAR-based cell therapy to treat cancer
Earlier this week the CIRM ICOC Board awarded $14.5 million to fund three translational stage research projects (TRAN1), whose goal is to support early development activities necessary for advancement to a clinical study or broad end use of a potential therapy. Although all three projects have their distinct area of focus, they all utilize CAR-based … Continue reading Latest CIRM TRAN1 awards focus on CAR-based cell therapy to treat cancer
Scientists develop faster, smarter way to classify tumors using single-cell technology
Dr. Stephen Lin, CIRM Senior Science Officer By Dr. Stephen Lin Single-cell. It is the new buzzword in biology. Single-cell biology refers to the in-depth characterization of individual cells in an organ or similar microenvironment. Every organ, like the brain or heart, is composed of thousands to millions of cells. Single-cell biology breaks those organs … Continue reading Scientists develop faster, smarter way to classify tumors using single-cell technology
Charting a new course for stem cell research
What are the latest advances in stem cell research targeting cancer? Can stem cells help people battling COVID-19 or even help develop a vaccine to stop the virus? What are researchers and the scientific community doing to help address the unmet medical needs of underserved communities? Those are just a few of the topics being … Continue reading Charting a new course for stem cell research
New CAR-T cell therapy using scorpion venom developed to treat brain tumors
Contributed by Wikimedia Commons (Public Domain) Glioblastoma (GBM) is an aggressive form of cancer that begins in the brain and results in tumors that can be very difficult to treat. This condition has claimed the lives of Beau Biden, former Vice President Joe Biden's son, and John McCain, former Senator of Arizona. However, a new … Continue reading New CAR-T cell therapy using scorpion venom developed to treat brain tumors
Two studies identify a molecule that could be used to block Zika virus and kill cancer cells
Dr. Tariq Rana (left) and Dr. Jeremy Rich (right) both lead independent teams at UC San Diego that identified a molecule, αvβ5 integrin, as the Zika virus' key to getting into brain stem cells Zika virus is caused by a virus transmitted by Aedes mosquitoes. People usually develop mild symptoms that include fever, rash, and … Continue reading Two studies identify a molecule that could be used to block Zika virus and kill cancer cells
Drug used to treat multiple sclerosis may improve glioblastoma outcomes
Dr. Jeremy Rich, UC San Diego Glioblastoma is an aggressive form of cancer that invades brain tissue, making it extremely difficult to treat. Current therapies involving radiation and chemotherapy are effective in destroying the bulk of brain cancer cells, but they are not able to reach the brain cancer stem cells, which have the ability … Continue reading Drug used to treat multiple sclerosis may improve glioblastoma outcomes
California gets first royalty check from Stem Cell Agency investments
CIRM recently shared in a little piece of history. The first royalty check, based on CIRM’s investment in stem cell research, was sent to the California State Treasurer’s office from City of Hope. It’s the first of what we hope will be many such checks, helping repay, not just the investment the state made in … Continue reading California gets first royalty check from Stem Cell Agency investments
Novel approach to slowing deadly brain cancer stem cells may lead to new treatments
Glioblastoma, a form of brain cancer, is one of the most dreaded cancer diagnoses. Standard radiation and chemotherapy treatments for glioblastoma almost always prove ineffective because of the cancer’s ability to grow back. With their unlimited potential to self-renew, cancer stem cells within the brain tumor are thought to be responsible for its aggressive reoccurrence. … Continue reading Novel approach to slowing deadly brain cancer stem cells may lead to new treatments
The Stem Cellar 