Starting a clinical trial is like taking a step into the unknown. It’s moving a potential therapy out of the lab and testing it in people. To reach this point the researchers have done a lot of work trying to ensure the therapy is safe. But that work was done in the lab, and on … Continue reading Clearing the first hurdle: spinal cord injury trial passes safety review
embryonic stem cells
Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see
“A pale hue”. For most of us that is a simple description, an observation about color. For Kristin Macdonald it’s a glimpse of the future. In some ways it’s a miracle. Kristin lost her sight to retinitis pigmentosa (RP). For many years she was virtually blind. But now, thanks to a clinical trial funded by … Continue reading Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see
Unlocking the secrets of how stem cells decide what kind of cell they’re going to be
Before joining CIRM I thought OCT4 was a date on the calendar. But a new study says it may be a lot closer to a date with destiny, because this study says OCT4 helps determine what kinds of cell a stem cell will become. Now, before we go any further I should explain for people … Continue reading Unlocking the secrets of how stem cells decide what kind of cell they’re going to be
Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury
A healthy T cell Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Directing the creation of T cells. To paraphrase the GOP Presidential nominee, any sane person LOVES, LOVES LOVES their T cells, … Continue reading Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury
CIRM Board targets diabetes and kidney disease with big stem cell research awards
A recent study estimated there may be more than 500 million people worldwide who have diabetes. That’s an astounding figure and makes diabetes one of the largest chronic disease epidemics in human history. One of the most serious consequences of untreated or uncontrolled diabetes is kidney damage. That can lead to fatigue, weakness, confusion, kidney … Continue reading CIRM Board targets diabetes and kidney disease with big stem cell research awards
The Spanish Inquisition and a tale of two stem cell agencies
Monty Python's Spanish Inquisition sketch: Photo courtesy Daily Mail UK It’s not often an article on stem cell research brings the old, but still much loved, British comedy series Monty Python into the discussion but a new study in the journal Cell Stem Cell does just that, comparing the impact of CIRM and the UK’s … Continue reading The Spanish Inquisition and a tale of two stem cell agencies
Approach that inspires DREADD could create new way to treat Parkinson’s disease
Dopamine producing brain nerve cells, made from embryonic stem cells Imagine having a treatment for Parkinson’s that acts like a light switch, enabling you to turn it on or off depending on your needs. Well, that’s what researchers at the University of Wisconsin-Madison have come up with. And if it works, it might help change … Continue reading Approach that inspires DREADD could create new way to treat Parkinson’s disease
Patient Advocates find their voice in a different language
Packed house for stem cell conference in Tokyo - Adrienne Shapiro front row, second from right One of the many wonderful things about travel is that it opens up your eyes and mind to the fact that, while there are many ways in which people around the world differ from each other, there are also … Continue reading Patient Advocates find their voice in a different language
How to handle CRISPR: Formulating a responsible approach to gene-editing
In February 2016, CIRM sponsored a workshop to discuss the impact of CRISPR, a gene-editing tool that is transforming stem cell research. The workshop was designed to enable the Standards Working Group (SWG) to reflect on policies governing the review and oversight of embryo research support by CIRM. After the workshop, we wrote a blog … Continue reading How to handle CRISPR: Formulating a responsible approach to gene-editing
New stem cell could offer new ways to study birth defects
You never know what you are going to find in the trash. For a group of intrepid researchers at Michigan State University their discovery could lead to new ways of studying birth defects and other reproductive problems. Because what they found in what’s normally considered cellular trash was a new kind of stem cell. The … Continue reading New stem cell could offer new ways to study birth defects
The Stem Cellar 