Senior author of the study Clive Svendsen, PhD (center) With funding support from the California Institute for Regenerative Medicine (CIRM), Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons … Continue reading CIRM-funded stem cell-gene therapy shows promise in ALS safety trial
Clive Svendsen
CIRM Board Approves New Clinical Trial for ALS
This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $11.99 million to Cedars-Sinai to fund a clinical trial for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a neurodegenerative disease that results in the death of nerve cells in the brain and spinal cord, causing … Continue reading CIRM Board Approves New Clinical Trial for ALS
200 years later, the search for a cure for Parkinson’s continues
On the surface, actor Michael J. Fox, singer Neil Diamond, civil rights activist Jesse Jackson and Scottish comedian Billy Connolly would appear to have little in common. Except for one thing. They all have Parkinson’s Disease (PD). Their celebrity status has helped raise public awareness about the condition, but studies show that awareness doesn’t amount … Continue reading 200 years later, the search for a cure for Parkinson’s continues
Stem Cells make the cover of National Geographic
National Geographic is one of those iconic magazines that everyone knows about but few people read. Which is a shame, because it's been around since 1888 and has helped make generations of readers aware about the world around them. And now, it's shifting gears and helping people know more about the world inside them. That's … Continue reading Stem Cells make the cover of National Geographic
A stepping stone for bringing stem cell therapy to patients with ALS
Imagine being told that you have a condition that gradually causes you to lose the ability to control your body movements, from picking up a pencil to walking to even breathing. Such is the reality for the nearly 6,000 people who are diagnosed with amyotrophic lateral sclerosis (ALS) every year, in the United States alone. … Continue reading A stepping stone for bringing stem cell therapy to patients with ALS
ALS is in the spotlight in CIRM’s “Ask the Expert About ALS & Stem Cells” Facebook Live event
American Football great Dwight Clark was renowned for having the safest hands in the game when he played for the San Francisco 49ers. But in September 2015 he was diagnosed with ALS (also known as Lou Gehrig’s disease) after not being able to use those hands to open a package of sugar. Less than three … Continue reading ALS is in the spotlight in CIRM’s “Ask the Expert About ALS & Stem Cells” Facebook Live event
Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is one of those conditions that a lot of people know about but don’t know a lot about. If they are fortunate it will stay that way. ALS is a nasty neurodegenerative disease that attacks motor neurons, the cells in the brain and spinal cord … Continue reading Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease
Tiny blood vessels in the brain can spur the growth of spinal motor neurons
Last week, researchers from Cedars-Sinai Medical Center added a new piece to the complex puzzle of what causes neurodegenerative disorders like amyotrophic lateral sclerosis (ALS). The team discovered that the tiny blood vessels in our brains do more than provide nutrients to and remove waste products from our brain tissue. It turns out that these … Continue reading Tiny blood vessels in the brain can spur the growth of spinal motor neurons
Can Stem Cell Therapies Help ALS Patients?
A scientist’s fifteen-year journey to develop a stem cell-based therapy that could one day help ALS patients. “Can stem cells help me Clive?” The sentence appeared slowly on a computer screen, each character separated by a pause while its author searched for the next character using a device controlled by his eye muscle. The person … Continue reading Can Stem Cell Therapies Help ALS Patients?
Stem cell agency funds Phase 3 clinical trial for Lou Gehrig’s disease
At CIRM we don’t have a disease hierarchy list that we use to guide where our funding goes. We don’t rank a disease by how many people suffer from it, if it affects children or adults, or how painful it is. But if we did have that kind of hierarchy you can be sure that … Continue reading Stem cell agency funds Phase 3 clinical trial for Lou Gehrig’s disease
The Stem Cellar 