Every year California performs around 100 kidney transplants in children but, on average, around 50 of these patients will have their body reject the transplant. These children then have to undergo regular dialysis while waiting for a new organ. Even the successful transplants require a lifetime of immunosuppression medications. These medications can prevent rejection but … Continue reading Making transplants easier for kids, and charting a new approach to fighting solid tumors.
cancer stem cells
Researchers discover promising approach against treatment-resistant cancer
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Photo: Albert Einstein College of Medicine Researchers at Albert Einstein College of Medicine have devised a promising strategy for overcoming a key cause of cancer deaths: the ability of cancer cells to thrive in the face of chemotherapy drugs designed to destroy them. There are cells, … Continue reading Researchers discover promising approach against treatment-resistant cancer
Old therapies inspire new hope for treatment of pediatric brain tumors
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Image courtesy St. Jude Children's Research Hospital A recent study led by John Hopkins Medicine has found that combining two 'old therapies' can offer a surprising new purpose - fighting Medulloblastoma, the most common malignant brain tumor in children. The fast-growing cancerous tumor originates in the brain … Continue reading Old therapies inspire new hope for treatment of pediatric brain tumors
De-stressing stem cells and the Bonnie & Clyde of stem cells
Dr. John Cashman The cells in our body are constantly signalling with each other, it's a critical process by which cells communicate not just with other cells but also with elements within themselves. One of the most important signalling pathways is called Wnt. This plays a key role in early embryonic and later development. But … Continue reading De-stressing stem cells and the Bonnie & Clyde of stem cells
Blocking pancreatic cancer stem cells
John Cashman Cancer stem cells are one of the main reasons why cancers are able to survive surgery, chemotherapy and radiation. They are able to hide from those therapies and, at a future date, emerge and spread the cancer in the body once again. Jionglia Cheng, PhD. Jionglia Cheng, PhD., the lead author of a … Continue reading Blocking pancreatic cancer stem cells
Newly developed biosensor can target leukemic stem cells
Dr. Michael Milyavsky (left) and his research student Muhammad Yassin (right). Image courtesy of Tel Aviv University. Every three minutes, one person in the United States is diagnosed with a blood cancer, which amounts to over 175,000 people every year. Every nine minutes, one person in the United States dies from a blood cancer, which … Continue reading Newly developed biosensor can target leukemic stem cells
71 for Proposition 71
Proposition 71 is the state ballot initiative that created California's Stem Cell Agency. This month, the Agency reached another milestone when the 71st clinical trial was initiated in the CIRM Alpha Stem Cell Clinics (ASCC) Network. The ASCC Network deploys specialized teams of doctors, nurses and laboratory technicians to conduct stem cell clinical trials at … Continue reading 71 for Proposition 71
How Tom Howing turned to stem cells to battle back against a deadly cancer
As we enter the new year, CIRM’s 2017 Annual Report will be posted in less than two weeks! Here’s one of the people we are profiling in the report, a patient who took part in a CIRM-funded clinical trial. In March of 2015, Tom Howing was diagnosed with stage 4 cancer. Over the next 18 … Continue reading How Tom Howing turned to stem cells to battle back against a deadly cancer
Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
Colon cancer is a global killer. Each year more than one million people worldwide are diagnosed with it; more than half a million die from it. If diagnosed early enough the standard treatment involves surgery, chemotherapy, radiation or targeted drug therapy to destroy the tumors. In many cases this may work. But in some cases, … Continue reading Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
Stem Cell Stories That Caught Our Eye: Three new ways to target cancer stem cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Targeting cancer stem cells. This week, three studies came out with novel ways for targeting cancer stem cells in different types of cancers. Here’s a … Continue reading Stem Cell Stories That Caught Our Eye: Three new ways to target cancer stem cells
The Stem Cellar 