Promising Advances in Alzheimer’s Research Could Create More Advanced Therapy Options

New developments in Alzheimer’s research are bringing us closer to more precise therapies for this debilitating disease. Alzheimer’s disease, is characterized by the formation of amyloid plaques in the brain, which interfere with the normal communication flow between brain cells, leading to debilitating symptoms like memory loss and impaired decision-making. These plaques are made out … Continue reading Promising Advances in Alzheimer’s Research Could Create More Advanced Therapy Options

New stem cell technique gives brain support cells a starring role

Astrocytes are some of the most common cells in the brain and central nervous system but they often get overlooked because they play a supporting role to the more glamorous neurons (even though they outnumber them around 50 to 1). But a new way of growing those astrocytes outside the brain could help pave the … Continue reading New stem cell technique gives brain support cells a starring role

Using stem cells to fix bad behavior in the brain

  Diseases of the brain have many different names, from Alzheimer’s and Parkinson’s to ALS and Huntington’s, but they often have similar causes. Researchers at the Gladstone Institutes in San Francisco are using that knowledge to try and find an approach that might be effective against all of these diseases. In a new CIRM-funded study, … Continue reading Using stem cells to fix bad behavior in the brain

Translating great stem cell ideas into effective therapies

In science, there are a lot of terms that could easily mystify people without a research background; “translational” is not one of them. Translational research simply means to take findings from basic research and advance them into something that is ready to be tested in people in a clinical trial. Yesterday our Governing Board approved … Continue reading Translating great stem cell ideas into effective therapies

What’s Fat Got to do With Alzheimer’s?

Diets these days are a dime a dozen, and dietary trends come and go. First eggs were “out” because they contain cholesterol, but now they are back “in” because we now know that some types of cholesterol can be actually good for the body. Then there was the era of “fat-free” or “reduced-fat” foods. This … Continue reading What’s Fat Got to do With Alzheimer’s?

2015 Golden Globes shines light on Alzheimer’s and ALS with acting awards

In between the one-liners, surprise presenters and bottomless champagne, something remarkable happened at last night’s 72nd Golden Globe Awards. 26 awards were given last night to the best in film and television. But two in particular were especially meaningful. I am referring, of course, to Julianne Moore and Eddie Redmayne, who each took home awards … Continue reading 2015 Golden Globes shines light on Alzheimer’s and ALS with acting awards

Bringing out the Big Guns: Scientists Weigh in on How Best to Combat Deadly Diseases of the Brain

Despite our best efforts, diseases of the brain are on the rise. Neurodegenerative conditions such as Alzheimer’s and Parkinson’s diseases threaten not only to devastate our aging population, but also cripple our economy. Meanwhile, the causes of conditions such as autism remain largely unknown. And brain and spinal cord injuries continue to increase—leaving their victims … Continue reading Bringing out the Big Guns: Scientists Weigh in on How Best to Combat Deadly Diseases of the Brain

Stories of Hope: Alzheimer’s Disease

This week on The Stem Cellar we feature some of our most inspiring patients and patient advocates as they share, in their own words, their Stories of Hope. Adele Miller knew what came next. She had lived it twice already: her father's unraveling, due to Alzheimer’s disease, and, a few years later, her mother's journey … Continue reading Stories of Hope: Alzheimer’s Disease

Blood Test Reveals Alzheimer’s Disease Risk, CIRM-Funded Study Finds

By the time someone begins to experience the clinical symptoms of Alzheimer’s disease, the damage has already been done. An accumulation of toxic proteins is causing brain cells to whither and die, taking with them a lifetime of precious memories. But what if we had a definitive test that could predict one’s risk of developing … Continue reading Blood Test Reveals Alzheimer’s Disease Risk, CIRM-Funded Study Finds

What was Old is New Again: Scientists Transplant Brain Cells into Aged Mice and Reverse Memory Loss

Alzheimer’s disease starts with small, almost imperceptible steps. And then it builds. Sometimes slowly over a period of decades, other times more quickly—in just a matter of years. But no matter the speed of progression, the end outcome is always the same. The sixth leading cause of death in the United State, Alzheimer’s develops as … Continue reading What was Old is New Again: Scientists Transplant Brain Cells into Aged Mice and Reverse Memory Loss