In science, there are a lot of terms that could easily mystify people without a research background; “translational” is not one of them. Translational research simply means to take findings from basic research and advance them into something that is ready to be tested in people in a clinical trial. Yesterday our Governing Board approved … Continue reading Translating great stem cell ideas into effective therapies
Stem cell research
A single protein can boost blood stem cell regeneration
Today, CIRM-funded scientists from the UCLA Broad Stem Cell Research Center reported in Nature Medicine that hematopoietic stem cells (HSCs) - blood stem cells that generate the cell in your blood and immune system - get a helping hand after injury from cells in the bone marrow called bone progenitor cells. By secreting a protein called dickkopf-1 … Continue reading A single protein can boost blood stem cell regeneration
Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Glowing stem cells help scientists understand how cells work. (Karen Ring) It’s easy to notice when something is going wrong. It’s a lot harder to … Continue reading Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
New iPS Insights: Cell Damage Enhances Reprogramming
Researchers learn a ton about the biological function of cells by studying them in vitro; that is, outside the body in a petri dish. But inside the body, or in vivo, cells respond to surrounding proteins and other cells that may be missing in an in vitro experiment. Important insights waiting to be revealed can … Continue reading New iPS Insights: Cell Damage Enhances Reprogramming
CIRM-funded stem cell trial for retinitis pigmentosa makes progress
A CIRM-funded clinical trial for retinitis pigmentosa (RP), a degenerative eye disease that causes blindness, recently reached its next milestone and announced the completion of its patient enrollment for a phase I/IIa study testing a stem cell derived therapy. This is a major step forward in determining whether this approach is both safe and effective … Continue reading CIRM-funded stem cell trial for retinitis pigmentosa makes progress
Seeing is Believing: New Video on the Power of Stem Cells
The world is full of skeptics. Remember when you first heard about self-driving cars? I’m sure that information was met with comments like, “When pigs fly!” or “I’ll believe it when I see it!” Well, it turns out that the best way to get people to believe something is possible, is to show them. And … Continue reading Seeing is Believing: New Video on the Power of Stem Cells
Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Horsing around at the World Stem Cell Summit The World Stem Cell Summit (WSCS) is coming up very shortly (December 6-9) in lovely downtown West Palm Beach, Florida. And this year it has an added attraction; horses. For my money the WSCS is the most enjoyable of the many conferences held around the US focusing … Continue reading Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Stem cell agency funds clinical trials in three life-threatening conditions
A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions
Throwback Thursday: Progress to a Cure for Type 1 Diabetes
Welcome back to our “Throwback Thursday” series on the Stem Cellar. Over the years, we’ve accumulated an arsenal of valuable stem cell stories on our blog. Some of these stories represent crucial advances towards stem cell-based cures for serious diseases and deserve a second look. This week in honor of Diabetes Awareness Month, we are … Continue reading Throwback Thursday: Progress to a Cure for Type 1 Diabetes
First spinal cord injury trial patient gets maximum stem cell dose
There comes a pivotal point in every experiment where you say “ok, now we are going to see if this really works.” We may be at that point in the clinical trial we are funding to see if stem cells can help people with spinal cord injuries. Today Asterias Biotherapeutics announced they have given the … Continue reading First spinal cord injury trial patient gets maximum stem cell dose
The Stem Cellar 