Welcome back to our “Throwback Thursday” series on the Stem Cellar. Over the years, we’ve accumulated an arsenal of exciting stem cell stories about advances towards stem cell-based cures for serious diseases. Today we’re featuring stories about the progress of CIRM-funded clinical trials for the treatment of a devastating, usually fatal, primary immune disease that … Continue reading Progress to a Cure for Bubble Baby Disease
Stem cell research
Using heart stem cells to help boys battling a deadly disorder
It’s hard to imagine how missing just one tiny protein can have such a devastating impact on a person. But with Duchenne Muscular Dystrophy (DMD) the lack of a single protein called dystrophin has deadly consequences. Now a new study is offering hope we may be able to help people with this rare genetic … Continue reading Using heart stem cells to help boys battling a deadly disorder
The life of a sleeping muscle stem cell is very busy
For biological processes, knowing when to slow down is as important as knowing when to step on the accelerator. Take for example muscle stem cells. In a healthy state, these cells mostly lay quiet and rarely divide but upon injury, they bolt into action by dividing and specializing into new muscle cells to help repair … Continue reading The life of a sleeping muscle stem cell is very busy
Using stem cells to take an inside approach to fixing damaged livers
Often on the Stem Cellar we write about work that is in a clinical trial. But getting research to that stage takes years and years of dedicated work. Over the next few months we are going to profile some of the scientists we fund who are doing Discovery, or early stage research, to highlight the … Continue reading Using stem cells to take an inside approach to fixing damaged livers
How a tiny patch of skin helped researchers save the life of a young boy battling a deadly disease
By any standards epidermolysis bullosa (EB) is a nasty disease. It’s a genetic condition that causes the skin to blister, break and tear off. At best, it’s painful and disfiguring. At worst, it can be fatal. Now researchers in Italy have come up with an approach that could offer hope for people battling the … Continue reading How a tiny patch of skin helped researchers save the life of a young boy battling a deadly disease
Stem cell-derived mini-intestines reveal bacteria’s key role in building up a newborn’s gut
The following factoid may induce an identity crisis for some people but it is true that our bodies carry more microbes than human cells. Some studies in 1970’s estimated the ratio at 10:1 though more recent calculations suggest we’re merely half microbe, half human. Because microbes are much smaller than human cells they make up … Continue reading Stem cell-derived mini-intestines reveal bacteria’s key role in building up a newborn’s gut
Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Some medical therapies have been around for so long that we naturally assume we understand how they work. That’s not always the case. Take aspirin for example. It’s been used for more than 4,000 years to treat pain and inflammation but it was only in the 1970’s that we really learned how it works. The … Continue reading Surprise findings about bone marrow transplants could lead to more effective stem cell therapies
Inspiring the next generation of stem cell scientists
“The technological breakthroughs that will be happening over the next few years – it’s your generation of scientists that will make this happen.” Dr. John Zaia, the Director of City of Hope’s Center for Gene Therapy, directed these words to a group of 55 talented high school students attending the 2017 CIRM SPARK meeting. SPARK … Continue reading Inspiring the next generation of stem cell scientists
A Patient Advocate’s Personal Manifesto
Janni Lehrer-Stein was just 26 when she was diagnosed with a degenerative eye disease and told she was going to be blind within six months. The doctor who gave her the news told her “But don’t worry, people like you are usually hit and killed by a bus long before they go completely blind.” At … Continue reading A Patient Advocate’s Personal Manifesto
Stanford scientists are growing brain stem cells in bulk using 3D hydrogels
This blog is the final installment in our #MonthofCIRM series. Be sure to check out our other blogs highlighting important advances in CIRM-funded research and initiatives. Neural stem cells from the brain have promising potential as cell-based therapies for treating neurological disorders such as Alzheimer’s disease, Parkinson’s, and spinal cord injury. A limiting factor preventing … Continue reading Stanford scientists are growing brain stem cells in bulk using 3D hydrogels
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