Cancer-causing mutations in blood stem cells may also link to heart disease

Whether we read about it in the news or hear it from our doctor, when we think about the causes of heart disease it’s usually some combination of inheriting bad genes from our parents and making poor life style choices like smoking or eating a diet high in fat and cholesterol. But in a fascinating … Continue reading Cancer-causing mutations in blood stem cells may also link to heart disease

Kidney Disease: There’s an Organ-on-a-Chip for That

“There’s an app for that” is a well-known phrase trademarked by Apple to promote how users can do almost anything they do on a computer on their mobile phone. Apps are so deeply ingrained in everyday life that it’s hard for some people to imagine living without them. (I know I’d be lost without google … Continue reading Kidney Disease: There’s an Organ-on-a-Chip for That

Stem cell stories that caught our eye: better ovarian cancer drugs, creating inner ear tissue, small fish big splash

Two drugs are better than one for ovarian cancer (Karen Ring). Earlier this week, scientists from UCLA reported that a combination drug therapy could be an effective treatment for 50% of aggressive ovarian cancers. The study was published in the journal Precision Oncology and was led by Dr. Sanaz Memarzadeh. Women with high-grade ovarian tumors … Continue reading Stem cell stories that caught our eye: better ovarian cancer drugs, creating inner ear tissue, small fish big splash

Stem cell stories that caught our eye: developing the nervous system, aging stem cells and identical twins not so identical

Here are the stem cell stories that caught our eye this week. Enjoy! New theory for how the nervous system develops. There’s a new theory on the block for how the nervous system is formed thanks to a study published yesterday by UCLA stem cell scientists in the journal Neuron. The theory centers around axons, thin … Continue reading Stem cell stories that caught our eye: developing the nervous system, aging stem cells and identical twins not so identical

Stem Cell Stories That Caught our Eye: Making blood and muscle from stem cells and helping students realize their “pluripotential”

Stem cells offer new drug for blood diseases. A new treatment for blood disorders might be in the works thanks to a stem cell-based study out of Harvard Medical School and Boston Children’s hospital. Their study was published in the journal Science Translational Medicine. The teams made induced pluripotent stem cells (iPSCs) from the skin … Continue reading Stem Cell Stories That Caught our Eye: Making blood and muscle from stem cells and helping students realize their “pluripotential”

Stories that caught our eye: frail bones in diabetics, ethics of future IVF, Alzheimer’s

The connection between diabetes and frail bones uncovered Fundamentally, diabetes is defined by abnormally high blood sugar levels. But that one defect over time carries an increased risk for a wide range of severe health problems. For instance, compared to healthy individuals, type 2 diabetics are more prone to poorly healing bone fractures – a … Continue reading Stories that caught our eye: frail bones in diabetics, ethics of future IVF, Alzheimer’s

Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID

Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Glowing stem cells help scientists understand how cells work. (Karen Ring) It’s easy to notice when something is going wrong. It’s a lot harder to … Continue reading Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID

Throwback Thursday: Progress to a Cure for Type 1 Diabetes

Welcome back to our “Throwback Thursday” series on the Stem Cellar. Over the years, we’ve accumulated an arsenal of valuable stem cell stories on our blog. Some of these stories represent crucial advances towards stem cell-based cures for serious diseases and deserve a second look. This week in honor of Diabetes Awareness Month, we are … Continue reading Throwback Thursday: Progress to a Cure for Type 1 Diabetes

From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes

Since the 1920s, insulin injections have remained the best solution for managing type 1 diabetes. Patients with this disease do not make enough insulin – a hormone that regulates the sugar levels in your blood – because the insulin-producing cells, or beta cells, in their pancreas are destroyed. Back then, it took two tons of … Continue reading From Pig Parts to Stem Cells: Scientist Douglas Melton Wins Ogawa-Yamanaka Prize for Work on Diabetes

Circular RNAs: the Mind-Boggling Dark Matter of the Human Genome

We were just a few hours into the 2016 annual meeting of the International Society for Stem Cell Research (ISSCR) yesterday afternoon and my mind was already blown away. Pier Paolo Pandolfi of the Beth Israel Deaconess Medical Center at Harvard, spoke during the first plenary session about circular RNAs, which he dubbed, “the mind-boggling … Continue reading Circular RNAs: the Mind-Boggling Dark Matter of the Human Genome