Getting old is an inevitable fact of life but what exactly causes it? One major hallmark of the aging process is cell senescence, in which cells gradually lose the ability to divide, leading to a breakdown in proper organ function. Adult stem cells that reside in our tissues usually spring into action to replenish cells … Continue reading Embryonic gene reverses old age in adult stem cells, in the lab
Disease Areas
Out of the mouths, or in this case hearts, of babes comes a hopeful therapy for heart attack patients
Lessons learned from babies with heart failure could now help adults Inspiration can sometimes come from the most unexpected of places. For English researcher Stephen Westaby it came from seeing babies who had heart attacks bounce back and recover. It led Westaby to a new line of research that could offer hope to people who … Continue reading Out of the mouths, or in this case hearts, of babes comes a hopeful therapy for heart attack patients
Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury
A healthy T cell Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Directing the creation of T cells. To paraphrase the GOP Presidential nominee, any sane person LOVES, LOVES LOVES their T cells, … Continue reading Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury
CIRM Board targets diabetes and kidney disease with big stem cell research awards
A recent study estimated there may be more than 500 million people worldwide who have diabetes. That’s an astounding figure and makes diabetes one of the largest chronic disease epidemics in human history. One of the most serious consequences of untreated or uncontrolled diabetes is kidney damage. That can lead to fatigue, weakness, confusion, kidney … Continue reading CIRM Board targets diabetes and kidney disease with big stem cell research awards
Researchers Identify Potential New Cell Source for Spinal Cord Injury Treatments
Now that Asterias Biotherapeutics’ CIRM-funded, stem cell-based clinical trial for spinal cord injury (SCI) has safely treated its first group of patients and begun recruiting the second, should other SCI researchers close up shop? Of course not. Since it’s a first-in-human trial, there certainly will be room for improvement even if the therapy proves successful. … Continue reading Researchers Identify Potential New Cell Source for Spinal Cord Injury Treatments
Advancing Stem Cell Research at the CIRM Bridges Conference
Where will stem cell research be in 10 years? What would you say to patients who wanted stem cell therapies now? What are the most promising applications for stem cell research? Why is it important for the government to fund regenerative medicine? These challenging and thought-provoking questions were posed to a vibrant group of undergraduate … Continue reading Advancing Stem Cell Research at the CIRM Bridges Conference
CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage
How retinitis pigmentosa erodes normal vision The failure rate for clinical trials is depressingly high. A study from Tufts University in 2010 found that for small molecules – the substances that make up more than 90 percent of the drugs on the market today – the odds of getting from a Phase 1 trial to … Continue reading CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage
Stem cell stories that caught our eye: herding stem cells, mini autistic brains, tendon repair and hair replacement
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Major advance in getting stem cells to behave. The promise of embryonic stem cells comes from their ability to become any cell type in the … Continue reading Stem cell stories that caught our eye: herding stem cells, mini autistic brains, tendon repair and hair replacement
Stem cell transplant offers Jake a glimpse of hope
Jake Javier surrounded by friends; Photo courtesy Julie Haener KTVU On Thursday, July 7th, Jake Javier became the latest member of a very select group. Jake underwent a stem cell transplant for a spinal cord injury at Santa Clara Valley Medical Center here in the San Francisco Bay Area. The therapy is part of the … Continue reading Stem cell transplant offers Jake a glimpse of hope
Salk Scientists Unlock New Secrets of Autism Using Human Stem Cells
Autism is a complex neurodevelopmental disorder whose mental, physical, social and emotional symptoms are highly variable from person to person. Because individuals exhibit different combinations and severities of symptoms, the concept of autism spectrum disorder (ASD) is now used to define the range of conditions. There are many hypotheses for why autism occurs in humans … Continue reading Salk Scientists Unlock New Secrets of Autism Using Human Stem Cells
The Stem Cellar 