In an average lifetime, the human heart dutifully beats more than 2.5 billion times. You can thank an area of the heart called the sinoatrial node, or SAN, which acts as the heart’s natural pacemaker. The SAN is made up of specialized heart muscle cells that, like a conductor leading an orchestra, dictates the rate … Continue reading Stem cell-derived pacemaker cells could help weak hearts keep the beat
Disease Areas
Brain Models Get an Upgrade: 3D Mini-Brains
Every year, companies like Apple, Microsoft and Google work tirelessly to upgrade their computer, software and smartphone technologies to satisfy growing demands for more functionality. Much like these companies, biomedical scientists work tirelessly to improve the research techniques and models they use to understand and treat human disease. Today, I’ll be talking about a cool … Continue reading Brain Models Get an Upgrade: 3D Mini-Brains
Stem Cell Stories that caught our eye: a womb with a view, reversing aging and stabilizing stem cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Today we bring you a trifecta of stem cell stories that were partially funded by grants from CIRM. A womb with a view: using 3D … Continue reading Stem Cell Stories that caught our eye: a womb with a view, reversing aging and stabilizing stem cells
Understanding two heart problems by studying the domino effect of one gene network
Although heart muscle cells, or cardiomyocytes, are specialized to help pump blood to the organs, they nonetheless carry all the genetic instructions for becoming a nerve cell, an intestinal cell, a liver or any cell type in the body. But at the moment in time that the fetal heart begins to develop, master switch proteins, … Continue reading Understanding two heart problems by studying the domino effect of one gene network
California’s stem cell agency rounds up the year with two more big hits
It’s traditional to end the year with a look back at what you hoped to accomplish and an assessment of what you did. By that standard 2016 has been a pretty good year for us at CIRM. Yesterday our governing Board approved funding for two new clinical trials, one to help kidney transplant patients, the … Continue reading California’s stem cell agency rounds up the year with two more big hits
With an eye toward 2020, CIRM looks at clinical milestones achieved in 2016
One year ago, CIRM announced its strategic plan for the next five years. It’s a bold vision to maximize our impact in stem cell research by accelerating stem cell treatments to patients with unmet medical needs. Our strategic plan, which can be found on our website, details how CIRM will invest in five main program … Continue reading With an eye toward 2020, CIRM looks at clinical milestones achieved in 2016
Stem cell stories that caught our eye: insights into stem cell biology through telomeres, reprogramming and lung disease
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Telomeres and stem cell stability: too much of a good thing Just like those plastic tips at the end of shoelaces (fun fact: they’re called … Continue reading Stem cell stories that caught our eye: insights into stem cell biology through telomeres, reprogramming and lung disease
How stem cells are helping change the face of medicine, one pioneering patient at a time
One of the many great pleasures of my job is that I get to meet so many amazing people. I get to know the researchers who are changing the face of medicine, but even more extraordinary are the people who are helping them do it, the patients. Attacking Cancer It’s humbling to meet people like … Continue reading How stem cells are helping change the face of medicine, one pioneering patient at a time
Translating great stem cell ideas into effective therapies
In science, there are a lot of terms that could easily mystify people without a research background; “translational” is not one of them. Translational research simply means to take findings from basic research and advance them into something that is ready to be tested in people in a clinical trial. Yesterday our Governing Board approved … Continue reading Translating great stem cell ideas into effective therapies
A single protein can boost blood stem cell regeneration
Today, CIRM-funded scientists from the UCLA Broad Stem Cell Research Center reported in Nature Medicine that hematopoietic stem cells (HSCs) - blood stem cells that generate the cell in your blood and immune system - get a helping hand after injury from cells in the bone marrow called bone progenitor cells. By secreting a protein called dickkopf-1 … Continue reading A single protein can boost blood stem cell regeneration
The Stem Cellar 