As a state agency we focus most of our efforts and nearly all our money on California. That’s what we were set up to do. But that doesn’t mean we don’t also look outside the borders of California to try and find the best research, and the most promising therapies, to help people in need. … Continue reading Partnering with the best to help find cures for rare diseases
Immune Disease
Rare diseases are not so rare
It seems like a contradiction in terms to say that there are nearly 7,000 diseases, affecting 30 million people, that are considered rare in the US. But the definition of a rare disease is one that affects fewer than 200,000 people and the National Institutes of Health’s (NIH) Genetic and Rare Diseases Information Center (GARD) … Continue reading Rare diseases are not so rare
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Glowing stem cells help scientists understand how cells work. (Karen Ring) It’s easy to notice when something is going wrong. It’s a lot harder to … Continue reading Stem cell stories that caught our eye: glowing stem cells and new insights into Zika and SCID
Stem cell agency funds clinical trials in three life-threatening conditions
A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions
Stem cell stories that caught our eye: better bone marrow transplants, turbo charging anti-inflammatory stem cells and Zika’s weapons
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Three steps to better BMT. Bone marrow stem cell transplants (BMT) save the lives of many thousands of patients every year, but they also kill … Continue reading Stem cell stories that caught our eye: better bone marrow transplants, turbo charging anti-inflammatory stem cells and Zika’s weapons
Advancing Stem Cell Research at the CIRM Bridges Conference
Where will stem cell research be in 10 years? What would you say to patients who wanted stem cell therapies now? What are the most promising applications for stem cell research? Why is it important for the government to fund regenerative medicine? These challenging and thought-provoking questions were posed to a vibrant group of undergraduate … Continue reading Advancing Stem Cell Research at the CIRM Bridges Conference
T cell fate and future immunotherapies rely on a tag team of genetic switches
Imagine if scientists could build microscopic smart missiles that specifically seek out and destroy deadly, hard-to-treat cancer cells in a patient’s body? Well, you don’t have to imagine it actually. With techniques such as chimeric antigen receptor (CAR) T therapy, a patient’s own T cells – immune system cells that fight off viruses and cancer … Continue reading T cell fate and future immunotherapies rely on a tag team of genetic switches
UCSF study explains how chronic inflammation impairs blood stem cell function
Inflammation is the immune system’s natural protective response to infection and injury. It involves the activation and mobilization of immune cells that can kill off foreign invaders and help repair damaged tissue. At the heart of the inflammatory response are hematopoietic stem cells (HSCs). These are blood stem cells found in the bone marrow that … Continue reading UCSF study explains how chronic inflammation impairs blood stem cell function
Scientists tackle aging by stabilizing defective blood stem cells in mice
Aging is an inevitable process that effects every cell, tissue, and organ in your body. You can live longer by maintaining a healthy, active lifestyle, but there is no magic pill that can prevent your body’s natural processes from slowly breaking down and becoming less efficient. As author Chinua Achebe would say, “Things Fall Apart”. … Continue reading Scientists tackle aging by stabilizing defective blood stem cells in mice
The Stem Cellar 