Stem Cell Image of the Week: Obesity-in-a-dish reveals mutations and abnormal function in nerve cells Our stem cell image of the week looks like the work of a pre-historic cave dweller who got their hands on some DayGlo paint. But, in fact, it’s a fluorescence microscopy image of stem cell-derived brain cells from the lab … Continue reading Stem Cell Roundup: The brain & obesity; iPSCs & sex chromosomes; modeling mental illness
Genetic Disorders
Stem Cell Round: Improving memory, building up “good” fat, nanomedicine
Stem Cell Photo of the Week In honor of brain awareness week, our featured stem cell photo is of the brain! Scientists at the Massachusetts General Hospital and Harvard Stem Cell Institute identified a genetic switch that could potentially improve memory during aging and symptoms of PTSD. Shown in this picture are dentate gyrus cells … Continue reading Stem Cell Round: Improving memory, building up “good” fat, nanomedicine
Just a Mom: The Journey of a Sickle Cell Disease Patient Advocate [video]
Adrienne Shapiro will tell you that she’s just a mom. And it’s true. She is just a mom. Just a mom who is the fourth generation of mothers in her family to have children born with sickle cell disease. Just a mom who was an early advocate of innovative stem cell and gene therapy research … Continue reading Just a Mom: The Journey of a Sickle Cell Disease Patient Advocate
A new study suggests CRISPR gene editing therapies should be customized for each patient
You know a scientific advance is a big deal when it becomes the main premise and title of a Jennifer Lopez-produced TV drama. That’s the case for CRISPR, a revolutionary gene-editing technology that promises to yield treatments for a wide range of genetic diseases. In fact, clinical trials using the CRISPR method are already underway … Continue reading A new study suggests CRISPR gene editing therapies should be customized for each patient
How a tiny patch of skin helped researchers save the life of a young boy battling a deadly disease
By any standards epidermolysis bullosa (EB) is a nasty disease. It’s a genetic condition that causes the skin to blister, break and tear off. At best, it’s painful and disfiguring. At worst, it can be fatal. Now researchers in Italy have come up with an approach that could offer hope for people battling the … Continue reading How a tiny patch of skin helped researchers save the life of a young boy battling a deadly disease
CIRM-Funded Clinical Trials Targeting Blood and Immune Disorders
This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Today we are featuring trials in our blood and … Continue reading CIRM-Funded Clinical Trials Targeting Blood and Immune Disorders
Stem cell stories that caught our eye: bubble baby therapy a go in UK, in-utero stem cell trial and novel heart disease target
There were lots of CIRM mentions in the news this week. Here are two brief recaps written by Karen Ring to get you up to speed. A third story by Todd Dubnicoff summarizes an promising finding related to heart disease by researchers in Singapore. CIRM-funded “bubble baby” disease therapy gets special designation by UK. … Continue reading Stem cell stories that caught our eye: bubble baby therapy a go in UK, in-utero stem cell trial and novel heart disease target
Bye Bye bubble baby disease: promising results from stem cell gene therapy trial for SCID
You don’t need to analyze any data to know for yourself that Evangelina Vaccaro’s experimental stem cell therapy has cured her of a devastating, often fatal disease of the immune system. All you have to do is look at a photo or video of her to see that she’s now a happy, healthy 5-year-old with a … Continue reading Bye Bye bubble baby disease: promising results from stem cell gene therapy trial for SCID
Stem Cell Profiles in Courage: Brenden Whittaker
It’s not often you meet someone who says one of their favorite things in the world is mowing the lawn. But then, there aren’t many people in the world like Brenden Whittaker. In fact, as of this writing, he may be unique. Brenden was born with severe chronic granulomatous disease (x-CGD), a rare genetic disorder … Continue reading Stem Cell Profiles in Courage: Brenden Whittaker
Cured by Stem Cells
To get anywhere you need a good map, and you need to check it constantly to make sure you are still on the right path and haven’t strayed off course. A year ago the CIRM Board gave us a map, a Strategic Plan, that laid out our course for the next five years. Our Annual … Continue reading Cured by Stem Cells
The Stem Cellar 