Type 1 diabetes is marked by a loss of insulin-producing beta cells in the pancreas. Without insulin, blood sugar can’t shuttle into the body’s energy-hungry organs and tissues. As a result, sugar accumulates in the blood which, over time, causes many serious complications such as kidney disease, heart disease and stroke. An over-reactive immune system … Continue reading Novel diabetes therapy uses stem cell “teachers” to calm immune cells
Diabetes
Stories that caught our eye: smelling weight gain, colon cancer & diet and diabetes & broken bones
How smelling your food could cause weight gain (Karen Ring). Here’s the headline that caught my eye this week: “Smelling your food first can make you fat…” It’s a bizarre statement, but the claim is backed by scientific research coming from a new study in Cell Metabolism by researchers at the University of California Berkeley. … Continue reading Stories that caught our eye: smelling weight gain, colon cancer & diet and diabetes & broken bones
Wall Street Journal features CIRM-funded clinical trials aiming for a diabetes cure
We think CIRM-funded clinical trials hold so much promise that it doesn’t surprise us when major news organizations publish stories about these projects that aim to provide stem cell treatments to patients with unmet medical needs. But we certainly don’t mind the attention! This past Saturday, for example, the Wall Street Journal featured two CIRM-funded … Continue reading Wall Street Journal features CIRM-funded clinical trials aiming for a diabetes cure
ViaCyte Advances Cell Replacement Therapy for High Risk Type 1 Diabetes
San Diego regenerative medicine company ViaCyte announced this week that the Food and Drug Administration (FDA) approved their Investigational New Drug (IND) Application for PEC-Direct, a cell-based therapy to treat patients at risk for severe complications caused by type 1 diabetes. In the US, IND approval is the final regulatory step required before a therapy … Continue reading ViaCyte Advances Cell Replacement Therapy for High Risk Type 1 Diabetes
Creating partnerships to help get stem cell therapies over the finish line
Trying to go it alone is never easy. Imagine how far Lewis would have got without Clark, or the two of them without Sacagawea. Would Batman have succeeded without Robin; Mickey without Minnie Mouse? Having a partner whose skills and expertise complements yours just makes things easier. That’s why some recent news about two CIRM-funded … Continue reading Creating partnerships to help get stem cell therapies over the finish line
Stem Cell Stories That Caught Our Eye: Plasticity in the pancreas and two cool stem cell tools added to the research toolbox
There’s more plasticity in the pancreas than we thought. You’re taught a lot of things about the world when you’re young. As you get older, you realize that not everything you’re told holds true and it’s your own responsibility to determine fact from fiction. This evolution in understanding happens in science too. Scientists do research … Continue reading Stem Cell Stories That Caught Our Eye: Plasticity in the pancreas and two cool stem cell tools added to the research toolbox
Stem cells stories that caught our eye: switching cell ID to treat diabetes, AI predicts cell fate, stem cell ALS therapy for Canada
Treating diabetes by changing a cell’s identity. Stem cells are an ideal therapy strategy for treating type 1 diabetes. That’s because the disease is caused by the loss of a very specific cell type: the insulin-producing beta cell in the pancreas. So, several groups are developing treatments that aim to replace the lost cells by transplanting … Continue reading Stem cells stories that caught our eye: switching cell ID to treat diabetes, AI predicts cell fate, stem cell ALS therapy for Canada
Partnering with the best to help find cures for rare diseases
As a state agency we focus most of our efforts and nearly all our money on California. That’s what we were set up to do. But that doesn’t mean we don’t also look outside the borders of California to try and find the best research, and the most promising therapies, to help people in need. … Continue reading Partnering with the best to help find cures for rare diseases
Stories that caught our eye: frail bones in diabetics, ethics of future IVF, Alzheimer’s
The connection between diabetes and frail bones uncovered Fundamentally, diabetes is defined by abnormally high blood sugar levels. But that one defect over time carries an increased risk for a wide range of severe health problems. For instance, compared to healthy individuals, type 2 diabetics are more prone to poorly healing bone fractures – a … Continue reading Stories that caught our eye: frail bones in diabetics, ethics of future IVF, Alzheimer’s
Don’t Sugar Coat it: A Patient’s Perspective on Type 1 Diabetes
“In the weeks leading up to my diagnosis, I remember making and drinking Kool-Aid at the rate of about a gallon per day, and getting up to pee and drink Kool-Aid several times a night. The exhaustion and constant thirst and the weight loss were pretty scary. Insulin saved my life, and it’s been saving … Continue reading Don’t Sugar Coat it: A Patient’s Perspective on Type 1 Diabetes
The Stem Cellar 