Harnessing the body’s immune system to tackle cancer

Often on the Stem Cellar we write about work that is in a clinical trial. But getting research to that stage takes years and years of dedicated work. Over the next few months, we are profiling some of the scientists we fund who are doing Discovery (early stage) and Translational (pre-clinical) research, to highlight the … Continue reading Harnessing the body’s immune system to tackle cancer

Scientists find switch that targets immunotherapies to solid tumors

Cancer immunotherapies harness the power of the patient’s own immune system to fight cancer. One type of immunotherapy, called adoptive T cell therapy, uses immune cells called CD8+ Killer T cells to target and destroy tumors. These T cells are made in the spleen and lymph nodes and they can migrate to different locations in … Continue reading Scientists find switch that targets immunotherapies to solid tumors

CIRM-Funded Research Makes Multiple Headlines this Week

When it rains it pours. This week, multiple CIRM-funded studies appeared in the news, highlighting the exciting progress our Agency is making towards funding innovative stem cell research and promoting the development of promising stem cell therapies for patients. Below are highlights. Fate Therapeutics Partners with UC San Diego to Develop Cancer Immunotherapy Last week, … Continue reading CIRM-Funded Research Makes Multiple Headlines this Week

Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out

When you have a life-changing, life-threatening disease, medical research never moves as quickly as you want to find a new treatment. Sometimes, as in the case of Parkinson’s disease, it doesn’t seem to move at all. At our Board meeting last week David Higgins, our Board member and Patient Advocate for Parkinson’s disease, made that … Continue reading Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out

Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies

When the immune system comes up as a topic in everyday conversation, it’s usually related to fighting off a cold or flu. While our immune cells certainly do detect and neutralize invading bacteria and viruses, they also play a critical role in killing abnormal, cancerous cells from within our bodies. “Don’t Eat Me” Signal 101 … Continue reading Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies

Stories that caught our eye: How dying cells could help save lives; could modified blood stem cells reverse diabetes?; and FDA has good news for patients, bad news for rogue clinics

Growing up I loved watching old cowboy movies. Invariably the hero, even though mortally wounded, would manage to save the day and rescue the heroine and/or the town. Now it seems some stem cells perform the same function, dying in order to save the lives of others. Researchers at Kings College in London were trying … Continue reading Stories that caught our eye: How dying cells could help save lives; could modified blood stem cells reverse diabetes?; and FDA has good news for patients, bad news for rogue clinics

Surprise findings about bone marrow transplants could lead to more effective stem cell therapies

Some medical therapies have been around for so long that we naturally assume we understand how they work. That’s not always the case. Take aspirin for example. It’s been used for more than 4,000 years to treat pain and inflammation but it was only in the 1970’s that we really learned how it works. The … Continue reading Surprise findings about bone marrow transplants could lead to more effective stem cell therapies

CIRM Board invests in three new stem cell clinical trials targeting arthritis, cancer and deadly infections

Every day at CIRM we get calls from people looking for a stem cell therapy to help them fight a life-threatening or life-altering disease or condition. One of the most common calls is about osteoarthritis, a painful condition where the cartilage that helps cushion our joints is worn away, leaving bone to rub on bone. … Continue reading CIRM Board invests in three new stem cell clinical trials targeting arthritis, cancer and deadly infections

CIRM-Funded Clinical Trials Targeting Cancers

Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers

CIRM Board Appoints Dr. Maria Millan as President and CEO

Yesterday was a big day for CIRM. Our governing Board convened for its September ICOC meeting and appointed Dr. Maria Millan as our new President and CEO. Dr. Millan has been serving as the Interim President/CEO since July, replacing former President Dr. Randal Mills. Dr. Millan has been at CIRM since 2012 and was instrumental … Continue reading CIRM Board Appoints Dr. Maria Millan as President and CEO