Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out

When you have a life-changing, life-threatening disease, medical research never moves as quickly as you want to find a new treatment. Sometimes, as in the case of Parkinson’s disease, it doesn’t seem to move at all. At our Board meeting last week David Higgins, our Board member and Patient Advocate for Parkinson’s disease, made that … Continue reading Hey, what’s the big idea? CIRM Board is putting up more than $16.4 million to find out

Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies

When the immune system comes up as a topic in everyday conversation, it’s usually related to fighting off a cold or flu. While our immune cells certainly do detect and neutralize invading bacteria and viruses, they also play a critical role in killing abnormal, cancerous cells from within our bodies. “Don’t Eat Me” Signal 101 … Continue reading Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies

Surprise findings about bone marrow transplants could lead to more effective stem cell therapies

Some medical therapies have been around for so long that we naturally assume we understand how they work. That’s not always the case. Take aspirin for example. It’s been used for more than 4,000 years to treat pain and inflammation but it was only in the 1970’s that we really learned how it works. The … Continue reading Surprise findings about bone marrow transplants could lead to more effective stem cell therapies

CIRM-Funded Clinical Trials Targeting Cancers

Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers

CIRM Board Appoints Dr. Maria Millan as President and CEO

Yesterday was a big day for CIRM. Our governing Board convened for its September ICOC meeting and appointed Dr. Maria Millan as our new President and CEO. Dr. Millan has been serving as the Interim President/CEO since July, replacing former President Dr. Randal Mills. Dr. Millan has been at CIRM since 2012 and was instrumental … Continue reading CIRM Board Appoints Dr. Maria Millan as President and CEO

Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day

Stopping brain cancer in its tracks. Scientists at Stanford Medicine discovered that you can halt aggressive brain cancers called high-grade gliomas by cutting off their supply of a signaling protein called neuroligin-3. Their research, which was funded by CIRM and the NIH, was published this week in the journal Nature.  The Stanford team, led by … Continue reading Stem Cell Stories That Caught Our Eye: Halting Brain Cancer, Parkinson’s disease and Stem Cell Awareness Day

Protein that turns normal cells into cancer stem cells offers target to fight colon cancer

Colon cancer is a global killer. Each year more than one million people worldwide are diagnosed with it; more than half a million die from it. If diagnosed early enough the standard treatment involves surgery, chemotherapy, radiation or targeted drug therapy to destroy the tumors. In many cases this may work. But in some cases, … Continue reading Protein that turns normal cells into cancer stem cells offers target to fight colon cancer

UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers

It’s not uncommon for biomedical institutes as well as their funding partners to announce through press releases that a clinical trial they’re running has gotten off the ground and has started to enroll patients. For an outsider looking in, it may seem like they’re jumping the gun a bit. No patients have received the therapy. … Continue reading UCLA launches CIRM-funded clinical trial using engineered blood stem cells to fight hard-to-treat cancers

Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor

An out of control flame can be very dangerous, even life-threatening. But when harnessed, that same flame sustains life in the form of warm air, a source of light, and a means to cook. A similar duality holds true for viruses. Once it infects the body, a virus can replicate like wildfire and cause serious … Continue reading Taming the Zika virus to kill cancer stem cells that drive lethal brain tumor

Confusing cancer to kill it

Confusion is not a state of mind that we usually seek out. Being bewildered is bad enough when it happens naturally, so why would anyone actively pursue it? But now some researchers are doing just that, using confusion to not just block a deadly blood cancer, but to kill it. Today the CIRM Board approved … Continue reading Confusing cancer to kill it