Dr. Mathew Blurton-Jones, leader of team that developed the chimeric "Mighty Mouse" model at the University of California, Irvine In ancient Greek mythology, a Chimera was a creature that was usually depicted as a lion with an additional goat head and a serpent for a tail. Due to the Chimera's animal hybrid nature, the term … Continue reading CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Alzheimer’s
Advancing stem cell research in many ways
Speakers at the Alpha Stem Cell Clinics Network Symposium: Photo by Marco Sanchez From Day One CIRM’s goal has been to advance stem cell research in California. We don’t do that just by funding the most promising research -though the 51 clinical trials we have funded to date clearly shows we do that rather well … Continue reading Advancing stem cell research in many ways
Media shine a spotlight on dodgy stem cell clinics
A doctor collects fat from a patient's back as part of an experimental stem cell procedure in Beverly Hills, Calif. on Dec. 5, 2014. (Raquel Maria Dillon / Associated Press) For several years now, we have been trying to raise awareness about the risks posed by clinics offering unproven or unapproved stem cell therapies. At … Continue reading Media shine a spotlight on dodgy stem cell clinics
The Sad Lane: How I navigated one of the happiest times of my life while my mom was losing hers to Alzheimer’s
In 1983 President Ronald Reagan named November as Alzheimer's Awareness month, to raise awareness about the growing impact the disease was having on Americans. At the time there were less than two million people with the disease. Today that number has grown to more than five million and is expected to reach 16 million by … Continue reading The Sad Lane: How I navigated one of the happiest times of my life while my mom was losing hers to Alzheimer’s
Stem Cell Roundup: Clinical Trial on the Horizon for Parkinson’s Disease, New Probe Targets Tricky Cancer Cells – Rare Brain Disease May Be Key to Alzheimer’s Insights
Stem Cell Image of the Week: This week's image shows dopamine producing brain cells. These are the cells that are depleted in people with Parkinson's Disease. Parkinson’s disease news: a new clinical trial, a new face of the disease (Kevin McCormack) In his long and illustrious career Alan Alda has worn many hats. First as the … Continue reading Stem Cell Roundup: Clinical Trial on the Horizon for Parkinson’s Disease, New Probe Targets Tricky Cancer Cells – Rare Brain Disease May Be Key to Alzheimer’s Insights
Promising Advances in Alzheimer’s Research Could Create More Advanced Therapy Options
New developments in Alzheimer’s research are bringing us closer to more precise therapies for this debilitating disease. Alzheimer’s disease, is characterized by the formation of amyloid plaques in the brain, which interfere with the normal communication flow between brain cells, leading to debilitating symptoms like memory loss and impaired decision-making. These plaques are made out … Continue reading Promising Advances in Alzheimer’s Research Could Create More Advanced Therapy Options
Using laughter to help find a treatment for Alzheimer’s
In 1983, when President Ronald Reagan designated an annual National Alzheimer’s Disease Awareness Month fewer than two million Americans had Alzheimer’s. Today, that number is close to 5.5 million and estimates suggest it will rise to 16 million by 2050. There are no treatments. No cure. But around the globe people are working hard to … Continue reading Using laughter to help find a treatment for Alzheimer’s
Friday Stem Cell Round: Ask the Expert Facebook Live, Old Brain Cells Reveal Insights and Synthetic Development
Stem Cell Photo of the Week: We’re Live on Facebook Live! Our stem cell photo of the week is a screenshot from yesterday’s Facebook Live event: “Ask the Expert: Stem Cells and Stroke”. It was our first foray into Facebook Live and, dare I say, it was a success with over 150 comments and 4,500 … Continue reading Friday Stem Cell Round: Ask the Expert Facebook Live, Old Brain Cells Reveal Insights and Synthetic Development
Building a better brain organoid
One of the reasons why it’s so hard to develop treatments for problems in the brain – things like Alzheimer’s, autism and schizophrenia - is that you can’t do an autopsy of a living brain to see what’s going wrong. People tend to object. To get around that, scientists have used stem cells to create … Continue reading Building a better brain organoid
Gladstone researchers tame toxic protein that carries increased Alzheimer’s risk
With a clinical trial failure rate of 99% over the past 15 years or so, the path to a cure for Alzheimer’s disease is riddled with disappointment. In many cases, candidate therapies looked very promising in pre-clinical animal studies, only to flop when tested in people. Now, a CIRM-funded Nature Medicine study by researchers at … Continue reading Gladstone researchers tame toxic protein that carries increased Alzheimer’s risk
The Stem Cellar 