It’s full steam ahead for the development of induced pluripotent stem cell (iPSC)-derived clinical trials. That’s according to a group at the National Human Genome Research Institute in Bethesda, Maryland who report this week in PNAS that the process of reprogramming a skin cell into the embryonic stem cell-like state of an iPSC does not … Continue reading “Apples to Apples” analysis: induced pluripotent stem cell (iPSC) method doesn’t increase mutations
Clinical Trials
Curing the Incurable through Definitive Medicine
“Curing the Incurable”. That was the theme for the first annual Center for Definitive and Curative Medicine (CDCM) Symposium held last week at Stanford University, in Palo Alto, California. The CDCM is a joint initiative amongst Stanford Healthcare, Stanford Children’s Health and the Stanford School of Medicine. Its mission is to foster an environment that … Continue reading Curing the Incurable through Definitive Medicine
Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
Stem cell transplants help put MS in remission: A combination of high dose immunosuppressive therapy and transplant of a person’s own blood stem cells seems to be a powerful tool in helping people with relapsing-remitting multiple sclerosis (RRMS) go into sustained remission. Multiple sclerosis (MS) is an autoimmune disorder where the body’s own immune system … Continue reading Stories that caught our eye: stem cell transplants help put MS in remission; unlocking the cause of autism; and a day to discover what stem cells are all about
A ‘Call to Action’ for change at the FDA
It’s bad enough to have to battle a debilitating and ultimately deadly disease like Huntington’s disease (HD). But it becomes doubly difficult and frustrating when you feel that the best efforts to develop a therapy for HD are running into a brick wall. That’s how patients and patient advocates working on HD feel as they … Continue reading A ‘Call to Action’ for change at the FDA
Stem Cells Profiles in Courage: Frank’s final gift
Not every story has a happy ending. But they do all have something to teach us. In the case of Frank St. Clair the lesson was simple: live life fully and freely, love those around you, and never give up. We were fortunate enough to get to know Frank as one of the people we … Continue reading Stem Cells Profiles in Courage: Frank’s final gift
Good news from Asterias’ CIRM-funded spinal cord injury trial
This week in the stem cell field, all eyes are on Asterias Biotherapeutics, a California-based company that’s testing a stem cell based-therapy in a CIRM-funded clinical trial for spinal cord injury patients. The company launched its Phase 1/2a clinical trial back in 2014 with the goal of determining the safety of the therapy and the … Continue reading Good news from Asterias’ CIRM-funded spinal cord injury trial
Stem Cell Profiles in Courage: Karl’s Fight with Cancer
When I think of a pioneer I have an image in my head of people heading west across the Americans plains in the 18th century, riding in a covered wagon pulled by weary oxen. Karl Trede doesn’t fit that image at all. He is a trim, elegant man who has a ready smile and a … Continue reading Stem Cell Profiles in Courage: Karl’s Fight with Cancer
Stem Cell Profiles in Courage: Brenden Whittaker
It’s not often you meet someone who says one of their favorite things in the world is mowing the lawn. But then, there aren’t many people in the world like Brenden Whittaker. In fact, as of this writing, he may be unique. Brenden was born with severe chronic granulomatous disease (x-CGD), a rare genetic disorder … Continue reading Stem Cell Profiles in Courage: Brenden Whittaker
Avalanches of exciting new stem cell research at the Keystone Symposia near Lake Tahoe
From January 8th to 13th, nearly 300 scientists and trainees from around the world ascended the mountains near Lake Tahoe to attend the joint Keystone Symposia on Neurogenesis and Stem Cells at the Resort at Squaw Creek. With record-high snowfall in the area (almost five feet!), attendees had to stay inside to stay warm and dry, … Continue reading Avalanches of exciting new stem cell research at the Keystone Symposia near Lake Tahoe
Stem Cells Profile in Courage: Pat Furlong, Patient Advocate
One of the true joys for me in helping put together this year’s Annual Report was getting to know the patients and patient advocates that we profiled in the report. These are some extraordinary individuals and the short profiles we posted only touch the surface of just how extraordinary. So, over the next few weeks … Continue reading Stem Cells Profile in Courage: Pat Furlong, Patient Advocate
The Stem Cellar 