What happens in a stroke When someone has a stroke, the blood flow to the brain is blocked. This kills some nerve cells and injures others. The damaged nerve cells are unable to communicate with other cells, which often results in people having impaired speech or movement. While ischemic and hemorrhagic strokes affect large blood … Continue reading Paving the way for a treatment for dementia
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Learning life lessons in the lab
Rohan Upadhyay, CIRM SPARK student 2021 One of the most amazing parts of an amazing job is getting to know the students who take part in CIRM’s SPARK (Summer Program to Accelerate Regenerative Medicine Knowledge) program. It’s an internship giving high school students, that reflect the diversity of California, a chance to work in a … Continue reading Learning life lessons in the lab
A conversation with Bob Klein about the past, present, and future of CIRM
Bob Klein Anyone who knows anything about CIRM knows about Bob Klein. He's the main author and driving force behind both Proposition 71 and Proposition 14, the voter-approved ballot initiatives that first created and then refunded CIRM. It's safe to say that without Bob, there'd be no CIRM. Recently, we had the great good fortune … Continue reading A conversation with Bob Klein about the past, present, and future of CIRM
City of Hope scientists use stem cells to develop ‘mini-brains’ to study Alzheimer’s and to test drugs in development
Alzheimer's is a progressive disease that destroys memory and other important mental functions. According to the non-profit HFC, co-founded by CIRM Board member Lauren Miller Rogen and her husband Seth Rogen, more than 5 million Americans are living with Alzheimer's. It is the 6th leading cause of death in the U.S and it is estimated … Continue reading City of Hope scientists use stem cells to develop ‘mini-brains’ to study Alzheimer’s and to test drugs in development
Scientists use stem cell ‘mini-brains’ to better understand signs of frontotemporal dementia
Dementia is a general term that describes a set of diseases that impair the ability to remember, think, or make decisions that interfere with doing everyday activities. According to the World Health Organization (WHO), around 50 million people worldwide have dementia with nearly 10 million new cases every year. Although it primarily affects older people … Continue reading Scientists use stem cell ‘mini-brains’ to better understand signs of frontotemporal dementia
Board Funds Fifteen Bridges to Stem Cell Research and Therapy Programs Across California and New Sickle Cell Disease Trial
Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $8.39 million to the University of California, San Francisco (UCSF) to fund a clinical trial for sickle cell disease (SCD). An additional $51.08 million was awarded to fifteen community colleges and universities across California to fund undergraduate and master’s level programs that … Continue reading Board Funds Fifteen Bridges to Stem Cell Research and Therapy Programs Across California and New Sickle Cell Disease Trial
UCSD researchers use stem cell model to better understand pregnancy complication
A team of UC San Diego researchers recently published novel preeclampsia models to aid in understanding this pregnancy complication that occurs in one of 25 U.S. pregnancies. Researchers include (left to right): Ojeni Touma, Mariko Horii, Robert Morey and Tony Bui. Credit: UC San Diego Pregnant women often tread uncertain waters in regards to their … Continue reading UCSD researchers use stem cell model to better understand pregnancy complication
Building a new mouse, one stem cell at a time
Science is full of acronyms. There are days where it feels like you need a decoder ring just to understand a simple sentence. A recent study found that between 1950 and 2019 researchers used more than 1.1 million unique acronyms in scientific papers. There’s even an acronym for three letter acronyms. It’s TLAs. Which of … Continue reading Building a new mouse, one stem cell at a time
Stem cell treatment improves motor function in monkeys modeling Parkinson’s Disease
Neurodegenerative diseases impact millions of people worldwide with the risk of being affected by one of these diseases increasing as you get older. For many of these diseases, there are very few treatments available to patients. As life expectancy increases and the population continues to age, it is crucial to try and find treatments that … Continue reading Stem cell treatment improves motor function in monkeys modeling Parkinson’s Disease
A new way to evade immune rejection in transplanting cells
Immune fluorescence of HIP cardiomyocytes in a dish; Photo courtesy of UCSF Transplanting cells or an entire organ from one person to another can be lifesaving but it comes with a cost. To avoid the recipient’s body rejecting the cells or organ the patient has to be given powerful immunosuppressive medications. Those medications weaken the … Continue reading A new way to evade immune rejection in transplanting cells
The Stem Cellar 