The DNA in our cells provide the instructions to make proteins, the workhorses of our body. Yet less than 2% of the 3 billion base pairs (the structural units of DNA) in each of our cells are actually involved in protein production. The rest, termed non-coding DNA for not being involved in protein production, has … Continue reading “Junk” DNA is development gold for the dividing embryo
Embryonic Stem Cells
Making stem cell-derived liver cells to study fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) affects approximately 30% of the population, with that number increasing to 75% in obese individuals. Shockingly, the number of cases is expected to increase 21% by the year 2030 in the United States alone. NAFLD refers to a broad range of liver conditions, which are all characterized by abnormally high … Continue reading Making stem cell-derived liver cells to study fatty liver disease
Stem Cell Roundup: Jake Javier’s amazing spirit; TV report highlights clinic offering unproven stem cell therapies
In the Roundup we usually focus on studies that highlight advances in stem cell research but today we’re going to do something a little different. Instead of relying on print for our stories, we’re turning to video. We begin with a piece about Jake Javier. Regular readers of our blog will remember that Jake is … Continue reading Stem Cell Roundup: Jake Javier’s amazing spirit; TV report highlights clinic offering unproven stem cell therapies
New findings about muscle stem cells reveals the potential for growing replacement organs
Chrissa Kioussi’s group at Oregon State University has made exciting advances in further unraveling the scientific mysteries of stem cells. In work detailed in Scientific Reports, this group found that muscle-specific stem cells actually have the ability to make multiple different cell types. Initially, this group was interested in understanding how gene expression changes during … Continue reading New findings about muscle stem cells reveals the potential for growing replacement organs
The moment of truth. A video about the stem cell therapy that could help millions of people going blind.
“No matter how much one prepares, the first patient is always something very special.” That’s how Dr. Mark Humayun describes his feelings as he prepared to deliver a CIRM-funded stem cell therapy to help someone going blind from dry age-related macular degeneration (AMD). Humayun, an ophthalmologist and stem cell researcher at USC, spent years developing … Continue reading The moment of truth. A video about the stem cell therapy that could help millions of people going blind.
Encouraging news about CIRM-funded clinical trial targeting vision loss
Dry age-related macular degeneration (AMD) is the leading cause of vision loss in the U.S. By 2020 it’s estimated that as many as three million Americans will be affected by the disease. Right now, there is no effective therapy. But that could change. A new CIRM-funded clinical trial is showing promise in helping people battling … Continue reading Encouraging news about CIRM-funded clinical trial targeting vision loss
Stem Cell Roundup: hESCs turn 20, tracking cancer stem cells, new ALS gene ID’d
Stem Cell Image of the Week This week’s stunning stem cell image is brought to you by researchers in the Brivanlou Lab at Rockefeller University. What looks like the center of a sunflower is actual a ball of neural rosettes derived from human embryonic stem cells (ESCs). Neural rosettes are structures that contain neural stem … Continue reading Stem Cell Roundup: hESCs turn 20, tracking cancer stem cells, new ALS gene ID’d
Stem Cell Patch Restores Vision in Patients with Age-Related Macular Degeneration
Two UK patients suffering from vision loss caused by age-related macular degeneration (AMD) have regained their sight thanks to a stem cell-based retinal patch developed by researchers from UC Santa Barbara (UCSB). The preliminary results of this promising Phase 1 clinical study were published yesterday in the journal Nature Biotechnology. AMD is one of the … Continue reading Stem Cell Patch Restores Vision in Patients with Age-Related Macular Degeneration
Stem Cell Roundup: No nerve cells for you, old man; stem cells take out the trash; clues to better tattoo removal
Stem cell image of the week: Do they or don’t they? The debate on new nerve cell growth in adult brain rages on. For the longest time, it was simply a given among scientists that once you reach adulthood, your brain’s neuron-making days were over. Then, over the past several decades, evidence emerged that the adult … Continue reading Stem Cell Roundup: No nerve cells for you, old man; stem cells take out the trash; clues to better tattoo removal
Breaking the isolation of rare diseases
How can something that affects 30 million Americans, one in ten people in the US, be called rare? But that’s the case with people who have a rare disease. There are around 7,000 different diseases that are categorized as rare because they affect fewer than 200,000 people. Less than five percent of these diseases have … Continue reading Breaking the isolation of rare diseases
The Stem Cellar 