Devising a drug safety measuring stick in stem cell-derived heart muscle cells One of the mantras in the drug development business is “fail early”. That’s because most of the costs of getting a therapy to market occur at the later stages when an experimental treatment is tested in clinical trials in people. So, it’s best … Continue reading Stem cell stories that caught our eye: drug safety for heart cells, worms hijack plant stem cells & battling esophageal cancer
Cancer Stem Cells
Stories that caught our eye: new target for killing leukemia cancer stem cells and stem cell vesicles halt glaucoma
New stem cell target for acute myeloid leukemia (Karen Ring). A new treatment for acute myeloid leukemia, a type of blood cancer that turns bone marrow stem cells cancerous, could be in the works in the form of a cancer stem cell destroying antibody. Scientists from the NYU Langone Medical Center and the Memorial Sloan … Continue reading Stories that caught our eye: new target for killing leukemia cancer stem cells and stem cell vesicles halt glaucoma
Stem Cell Profiles in Courage: Karl’s Fight with Cancer
When I think of a pioneer I have an image in my head of people heading west across the Americans plains in the 18th century, riding in a covered wagon pulled by weary oxen. Karl Trede doesn’t fit that image at all. He is a trim, elegant man who has a ready smile and a … Continue reading Stem Cell Profiles in Courage: Karl’s Fight with Cancer
Cured by Stem Cells
To get anywhere you need a good map, and you need to check it constantly to make sure you are still on the right path and haven’t strayed off course. A year ago the CIRM Board gave us a map, a Strategic Plan, that laid out our course for the next five years. Our Annual … Continue reading Cured by Stem Cells
Stem cell heroes: patients who had life-saving, life-changing treatments inspire CIRM Board
It’s not an easy thing to bring an entire Board of Directors to tears, but four extraordinary people and their families managed to do just that at the last CIRM Board meeting of 2016. The four are patients who have undergone life-saving or life-changing stem cell therapies that were funded by our agency. The … Continue reading Stem cell heroes: patients who had life-saving, life-changing treatments inspire CIRM Board
Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Horsing around at the World Stem Cell Summit The World Stem Cell Summit (WSCS) is coming up very shortly (December 6-9) in lovely downtown West Palm Beach, Florida. And this year it has an added attraction; horses. For my money the WSCS is the most enjoyable of the many conferences held around the US focusing … Continue reading Stem cell stories that caught our eye: Horse patients, Brain cancer stem cells, and a Bony Heart
Stem cell agency funds clinical trials in three life-threatening conditions
A year ago the CIRM Board unanimously approved a new Strategic Plan for the stem cell agency. In the plan are some rather ambitious goals, including funding ten new clinical trials in 2016. For much of the last year that has looked very ambitious indeed. But today the Board took a big step towards reaching … Continue reading Stem cell agency funds clinical trials in three life-threatening conditions
Stem cell stories that caught our eye: Salamander limb regrowth, mass producing cells for kidneys and halting cancer stem cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Fun with axolotls. Axolotls, the albino aquatic critters that look like they have feathers growing out of the backs of their heads, have long been … Continue reading Stem cell stories that caught our eye: Salamander limb regrowth, mass producing cells for kidneys and halting cancer stem cells
Sleep inducing hormone puts breast cancer cells to rest
It’s pretty easy to connect the dots between a lack of sleep and an increased risk of a deadly car crash. But what about an increased risk of cancer? A 2012 study of 101 women newly diagnosed with breast cancer found that those with inadequate sleep were more likely to have more aggressive tumors. Though … Continue reading Sleep inducing hormone puts breast cancer cells to rest
Stem cell stories that caught our eye: a surprising benefit of fasting, faster way to make iPSCs, unlocking the secret of leukemia cancer cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Is fasting the fountain of youth? Among the many insults our bodies endure in old age is a weakened immune system which leaves the elderly … Continue reading Stem cell stories that caught our eye: a surprising benefit of fasting, faster way to make iPSCs, unlocking the secret of leukemia cancer cells
The Stem Cellar 