De-stressing stem cells and the Bonnie & Clyde of stem cells

Dr. John Cashman The cells in our body are constantly signalling with each other, it's a critical process by which cells communicate not just with other cells but also with elements within themselves. One of the most important signalling pathways is called Wnt. This plays a key role in early embryonic and later development. But … Continue reading De-stressing stem cells and the Bonnie & Clyde of stem cells

Keeping intestinal stem cells in their prime

The average length of the human gut is 25 feet long. That’s equivalent to four really tall people or five really short people lined up head to toe. Intestinal stem cells have the fun job of regenerating and replacing ALL the cells that line the gut. Therefore, it’s important for these stem cells to be … Continue reading Keeping intestinal stem cells in their prime

Unlocking the secrets of how stem cells decide what kind of cell they’re going to be

Before joining CIRM I thought OCT4 was a date on the calendar. But a new study says it may be a lot closer to a date with destiny, because this study says OCT4 helps determine what kinds of cell a stem cell will become. Now, before we go any further I should explain for people … Continue reading Unlocking the secrets of how stem cells decide what kind of cell they’re going to be