Human induced pluripotent stem cell-derived cardiomyocytes (heart cells) shown in green and blue, are infected by the novel coronavirus SARS-CoV-2 (red). Image provided by Cedars-Sinai Board of Governors Regenerative Medicine Institute. There is still a lot that we don't understand about SARS-CoV-2 (COVID-19), the new coronavirus that has caused a worldwide pandemic. Some patients that … Continue reading Stem cells used to look at how COVID-19 attacks heart muscle
UCLA Broad Stem Cell Research Center
A ready-made approach to tackling COVID-19
Coronavirus particles, illustration. In late March the CIRM Board approved $5 million in emergency funding for COVID-19 research. The idea was to support great ideas from California’s researchers, some of which had already been tested for different conditions, and see if they could help in finding treatments or a vaccine for the coronavirus. Less than … Continue reading A ready-made approach to tackling COVID-19
Scientists Engineer Stem Cells to Fight HIV
Image of the virus that causes AIDS - courtesy NIH If that headline seems familiar it should. It came from an article in MIT Technology Review back in 2009. There have been many other headlines since then, all on the same subject, and yet here we are, in 2020, and still no cure for HIV/AIDS. … Continue reading Scientists Engineer Stem Cells to Fight HIV
Promising results from CIRM-funded projects
Severe Leukocyte Adhesion Deficiency-1 (LAD-1) is a rare condition that causes the immune system to malfunction and reduces its ability to fight off viruses and bacteria. Over time the repeated infections can take a heavy toll on the body and dramatically shorten a person’s life. But now a therapy, developed by Rocket Pharmaceuticals, is showing … Continue reading Promising results from CIRM-funded projects
Can stem cells help people who have had a stroke? Ask the experts.
Stroke is the third leading cause of death and disability in the US. Every 45 seconds someone in the US has a stroke. Every year around 275,000 people die from a stroke many more survive but are often impaired by the brain attack. The impact is not just physical, but psychological and emotional. It takes … Continue reading Can stem cells help people who have had a stroke? Ask the experts.
CIRM supported study finds that a gene associated with autism influences brain stem cells
Dr. Bennett Novitch, UCLA Broad Stem Cell Research CenterImage Credit: UCLA Broad Stem Cell Research Center In a previous blog post, we discussed new findings in a CIRM supported study at the Salk Institute for Autism Spectrum Disorder (ASD), a developmental disorder that comes in broad ranges and primarily affects communication and behavior. This week, … Continue reading CIRM supported study finds that a gene associated with autism influences brain stem cells
Stem Cell/Gene Therapy combo heals patients battling rare disorder
Brenden Whittaker and his dog: Photo by Colin McGuire A few years ago, Brenden Whittaker was running out of time. Brenden was born with a rare condition called x-linked chronic granulomatous disease or XCGD. It meant he lacked a critical part of his immune system that protects against bacterial or fungal infections. Over 22 years … Continue reading Stem Cell/Gene Therapy combo heals patients battling rare disorder
Boosting the blood system after life-saving therapy
Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right): Photo Courtesy UCLA Chemotherapy and radiation are two of the front-line weapons in treating cancer. They can be effective, even life-saving, but they can also be … Continue reading Boosting the blood system after life-saving therapy
CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Dr. Theodore Nowicki, physician in the division of pediatric hematology/oncology at UCLA. Photo courtesy of Milo Mitchell/UCLA Jonsson Comprehensive Cancer Center The governing Board of the California Institute for Regenerative Medicine (CIRM) awarded two grants totaling $11.15 million to carry out two new clinical trials. These latest additions bring the total number of CIRM funded … Continue reading CIRM Board Approves Funding for New Clinical Trials in Solid Tumors and Pediatric Disease
Stem Cell Roundup: Improving muscle function in muscular dystrophy; Building a better brain; Boosting efficiency in making iPSC’s
Here are the stem cell stories that caught our eye this week. Photos of the week TGIF! We’re so excited that the weekend is here that we are sharing not one but TWO amazing stem cell photos of the week. Photo #1 is borrowed from a blog we wrote earlier this week about a new … Continue reading Stem Cell Roundup: Improving muscle function in muscular dystrophy; Building a better brain; Boosting efficiency in making iPSC’s
The Stem Cellar 