Funding stem cell research targeting a rare and life-threatening disease in children

If you have never heard of cystinosis you should consider yourself fortunate. It’s a rare condition caused by an inherited genetic mutation. It hits early and it hits hard. Children with cystinosis are usually diagnosed before age 2 and are in end-stage kidney failure by the time they are 9. If that’s not bad enough … Continue reading Funding stem cell research targeting a rare and life-threatening disease in children

Salk scientists explain why brain cells are genetically diverse

I’ve always wondered why some sets of genetically identical twins become not so identical later in life. Sometimes they differ in appearance. Other times, one twin is healthy while the other is plagued with a serious disease. These differences can be explained by exposure to different environmental factors over time, but there could also be … Continue reading Salk scientists explain why brain cells are genetically diverse

Making a deposit in the Bank: using stem cells from children with rare diseases to find new treatments

Part of The Stem Cellar series on ten years of iPS cells For Chris Waters, the motivation behind her move from big pharmaceutical companies and biotech to starting a non-profit organization focused on rare diseases in children is simple: “What’s most important is empowering patient families and helping them accelerate research to the clinical solutions … Continue reading Making a deposit in the Bank: using stem cells from children with rare diseases to find new treatments

Young man with spinal cord injury regains use of hands and arms after stem cell therapy

Hope is such a fragile thing. We cling to it in bad times. It offers us a sense that we can bear whatever hardships we are facing today, and that tomorrow will be better. Kris Boesen knows all about holding on to hope during bad times. On March 6th of this year he was left … Continue reading Young man with spinal cord injury regains use of hands and arms after stem cell therapy

Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see

“A pale hue”. For most of us that is a simple description, an observation about color. For Kristin Macdonald it’s a glimpse of the future. In some ways it’s a miracle. Kristin lost her sight to retinitis pigmentosa (RP). For many years she was virtually blind. But now, thanks to a clinical trial funded by … Continue reading Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see

Out of the mouths, or in this case hearts, of babes comes a hopeful therapy for heart attack patients

Lessons learned from babies with heart failure could now help adults Inspiration can sometimes come from the most unexpected of places. For English researcher Stephen Westaby it came from seeing babies who had heart attacks bounce back and recover. It led Westaby to a new line of research that could offer hope to people who … Continue reading Out of the mouths, or in this case hearts, of babes comes a hopeful therapy for heart attack patients

Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury

A healthy T cell Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Directing the creation of T cells. To paraphrase the GOP Presidential nominee, any sane person LOVES, LOVES LOVES their T cells, … Continue reading Stem cell stories that caught our eye: turning on T cells; fixing our brains; progress and trends in stem cells; and one young man’s journey to recover from a devastating injury

Helping stem cells sleep can boost their power to heal

Mighty mouse muscle cells We are often told that sleep is one of the most important elements of a healthy lifestyle, that it helps in the healing and repair of our heart and blood vessels – among other things. It turns out that sleep, or something very similar, is equally important for stem cells, helping … Continue reading Helping stem cells sleep can boost their power to heal

A Dream made me change my mind. Almost.

Dream Alliance: photo courtesy Daily Telegraph, UK On Friday I was faced with the real possibility that a horse had made an ass out of me. Over the years we have written many articles about the risks of unproven stem cell therapies, treatments that have not yet been shown in clinical trials to be safe … Continue reading A Dream made me change my mind. Almost.

Approach that inspires DREADD could create new way to treat Parkinson’s disease

Dopamine producing brain nerve cells, made from embryonic stem cells Imagine having a treatment for Parkinson’s that acts like a light switch, enabling you to turn it on or off depending on your needs. Well, that’s what researchers at the University of Wisconsin-Madison have come up with. And if it works, it might help change … Continue reading Approach that inspires DREADD could create new way to treat Parkinson’s disease