Immune fluorescence of HIP cardiomyocytes in a dish; Photo courtesy of UCSF Transplanting cells or an entire organ from one person to another can be lifesaving but it comes with a cost. To avoid the recipient’s body rejecting the cells or organ the patient has to be given powerful immunosuppressive medications. Those medications weaken the … Continue reading A new way to evade immune rejection in transplanting cells
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A guide to healing
Dr. Evan Snyder Having grown up in an era where to find your way around you had to use paper maps, a compass and a knowledge of the stars (OK, I’m not actually that old!) I’m forever grateful to whoever invented the GPS. It’s a lifesaver, and I daresay has also saved more than a … Continue reading A guide to healing
Lab-grown human sperm cells could unlock treatments for infertility
Dr. Miles Wilkinson: Photo courtesy UCSD Out of 100 couples in the US, around 12 or 13 will have trouble starting a family. In one third of those cases the problem is male infertility (one third is female infertility and the other third is a combination of factors). In the past treatment options for men … Continue reading Lab-grown human sperm cells could unlock treatments for infertility
A recap on last week: two gut wrenching studies
Fluorescent pictures of a human colon organoidImage credit: Dr Thierry Jarde With everyone stocking up on food essentials this past week, it brings to mind the vital role that our stomach plays in order to properly digest these foods. This week, we wanted to share two separate studies related to aspects of the gut. Promising … Continue reading A recap on last week: two gut wrenching studies
Researchers create “xenobot” – world’s first living, self-healing robots created from frog stem cells
Artificial Intelligence methods automatically design diverse candidate lifeforms in simulation (top row) to perform some desired function, and transferable designs are then created using a cell-based construction toolkit to realize living systems (bottom row) with the predicted behaviors. Image credit: https://cdorgs.github.io/ The thought of microscopic robots brings the image of Hollywood blockbusters such as "Terminator" … Continue reading Researchers create “xenobot” – world’s first living, self-healing robots created from frog stem cells
From organs to muscle tissue: how stem cells are being used in 3D
A Sunday Afternoon on the Island of La Grande Jatte by Georges-Pierre Seurat When most people think of stem cells, they might conjure up an image of small dots under a microscope. It is hard to imagine these small specs being applied to three-dimensional structures. But like a pointillism painting, such as A Sunday Afternoon … Continue reading From organs to muscle tissue: how stem cells are being used in 3D
Stem cell stories that caught our eye: update on Capricor’s heart attack trial; lithium on the brain; and how stem cells do math
Today our partners Capricor Therapeutics announced that its stem cell therapy for patients who have experienced a large heart attack is unlikely to meet one of its key goals, namely reducing the scar size in the heart 12 months after treatment. The news came after analyzing results from patients at the halfway point of the … Continue reading Stem cell stories that caught our eye: update on Capricor’s heart attack trial; lithium on the brain; and how stem cells do math
Scientists make stem cell-derived nerve cells damaged in spinal cord injury
The human spinal cord is an information highway that relays movement-related instructions from the brain to the rest of the body and sensory information from the body back to the brain. What keeps this highway flowing is a long tube of nerve cells and support cells bundled together within the spine. When the spinal cord … Continue reading Scientists make stem cell-derived nerve cells damaged in spinal cord injury
Using stem cells to fix bad behavior in the brain
Diseases of the brain have many different names, from Alzheimer’s and Parkinson’s to ALS and Huntington’s, but they often have similar causes. Researchers at the Gladstone Institutes in San Francisco are using that knowledge to try and find an approach that might be effective against all of these diseases. In a new CIRM-funded study, … Continue reading Using stem cells to fix bad behavior in the brain
The Stem Cellar 