Neurodegenerative diseases impact millions of people worldwide with the risk of being affected by one of these diseases increasing as you get older. For many of these diseases, there are very few treatments available to patients. As life expectancy increases and the population continues to age, it is crucial to try and find treatments that … Continue reading Stem cell treatment improves motor function in monkeys modeling Parkinson’s Disease
Nature Medicine
Stanford scientists link problems in nerve cells to schizophrenia
A spherical cluster of hundreds of thousands of brain cells cultured in a lab dish. A team of researchers studied such neuronal clusters to better understand schizophrenia.Image Credit: Pasca lab The neurological origins of mental illness continue to remain a mystery and along with it any potential treatments for these conditions. However, Dr. Sergiu Pasca … Continue reading Stanford scientists link problems in nerve cells to schizophrenia
Stem Cell/Gene Therapy combo heals patients battling rare disorder
Brenden Whittaker and his dog: Photo by Colin McGuire A few years ago, Brenden Whittaker was running out of time. Brenden was born with a rare condition called x-linked chronic granulomatous disease or XCGD. It meant he lacked a critical part of his immune system that protects against bacterial or fungal infections. Over 22 years … Continue reading Stem Cell/Gene Therapy combo heals patients battling rare disorder
Researchers create a better way to grow blood stem cells
UCLA's Dr. Hanna Mikkola and Vincenzo Calvanese, lead scientists on the study. Photo courtesy UCLA Blood stem cells are a vital part of us. They create all the other kinds of blood cells in our body and are used in bone marrow transplants to help people battling leukemia or other blood cancers. The problem is … Continue reading Researchers create a better way to grow blood stem cells
Transplanted stem cells used to grow fully functional lungs in mice
Illustration of a human lung According to organ donation statistics from the Health Resources & Services Administration, over 113,000 men, women, and children are on the national transplant waiting list as of July 2019. Another person is added to the waiting list every 10 minutes and 20 people die each day waiting for a transplant. … Continue reading Transplanted stem cells used to grow fully functional lungs in mice
3D brain model shows potential for treatment of hypoxic brain injuries in infants
Image of 3D brain cultures in the Sergiu Pasca lab. Photo courtesy of Timothy Archibald. A baby's time in the womb is one of the most crucial periods in terms of its development. The average length of gestation, which is defined as the amount of time in the womb from conception to birth, is approximately … Continue reading 3D brain model shows potential for treatment of hypoxic brain injuries in infants
Using 3D printer to develop treatment for spinal cord injury
Spinal cord injuries (SCIs) affect approximately 300,000 Americans, with about 18,000 new cases occurring per year. One of these patients, Jake Javier, who we have written about many times over the past several years, received ten million stem cells as part of a CIRM-funded clinical trial and a video about his first year at Cal … Continue reading Using 3D printer to develop treatment for spinal cord injury
New approach could help turn back the clock and reverse damage for stroke patients
Stroke is the leading cause of serious, long-term disability in the US. Every year almost 800,000 people suffer from a stroke. The impact on their lives, and the lives of those around them can be devastating. Right now the only treatment approved by the US Food and Drug Administration (FDA) is tissue plasminogen activator or … Continue reading New approach could help turn back the clock and reverse damage for stroke patients
Stem cells could offer hope for deadly childhood muscle wasting disease
Duchenne muscular dystrophy (DMD) is a particularly nasty rare and fatal disease. It predominantly affects boys, slowly robbing them of their ability to control their muscles. By 10 years of age, boys with DMD start to lose the ability to walk; by 12, most need a wheelchair to get around. Eventually they become paralyzed, and … Continue reading Stem cells could offer hope for deadly childhood muscle wasting disease