Here’s a heartfelt science story for all those Valentine’s day fans out there. Scientists from the Gladstone Institutes have identified how a group of transcription factors interact during embryonic development to make a healthy heart. Their work will increase our biological understanding of how the heart is formed and could produce new methods for treating … Continue reading A cardiac love triangle: how transcription factors interact to make a heart
heart disease
CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart
As part of our CIRM scholar series, we feature the research accomplishments of students and postdocs that have received CIRM funding. I’d like to introduce you to one of our CIRM Scholars, Jessica Gluck. She’s currently a Postdoctoral Fellow at UC Davis working on human stem cell models of heart development. Jessica began her education … Continue reading CIRM Scholar Jessica Gluck on using stem cells to make biological pacemakers for the heart
Regenerating damaged muscle after a heart attack
Images of clusters of heart muscle cells (in red and green) derived from human embryonic stem cells 40 days after transplantation. Courtesy UCLA Every year more than 735,000 Americans have a heart attack. Many of those who survive often have lasting damage to their heart muscle and are at increased risk for future attacks and … Continue reading Regenerating damaged muscle after a heart attack
Patching up a Broken Heart with FSTL1
How do you mend a broken heart? It’s a subject that songwriters have pondered for generations, without success. But if you pose the same question to a heart doctor, they would give you a number of practical options that focus on the prevention or management of the physical symptoms you are dealing with. That’s because … Continue reading Patching up a Broken Heart with FSTL1
10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials
In 2004, when 59 percent of California voters approved the creation of CIRM, our state embarked on an unprecedented experiment: providing concentrated funding to a new, promising area of research. The goal: accelerate the process of getting therapies to patients, especially those with unmet medical needs. Having 10 potential treatments expected to be approved for … Continue reading 10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials
Cells’ Knack for Hoarding Proteins Inadvertently Kickstarts the Aging Process
Even cells need to take out the trash in order to maintain a healthy clean environment. And scientists are now uncovering the harmful effects when cells instead begin to hoard their garbage. Aging, on the cellular level is—at its core—the increasing inability for cells to repair themselves over time. As cells begin to break down … Continue reading Cells’ Knack for Hoarding Proteins Inadvertently Kickstarts the Aging Process
Finding your Inner Rhythm: Cedars-Sinai Cardiologists Create Biological “Pacemakers” in the Heart
If your heart has trouble keeping a steady rhythm, you normally get a pacemaker: a small device that is inserted into your body and attached to your heart. About 300,000 people receive a pacemaker each year. But what if we could harness the body’s own cells to do what an external device does today? In … Continue reading Finding your Inner Rhythm: Cedars-Sinai Cardiologists Create Biological “Pacemakers” in the Heart
BIO International Panel Showed Stem Cell Science Poised to Make a Difference in Medical Practice Soon
When the biotechnology trade association began holding annual conferences in 1993, they drew 1,400 to the first event. This year BIO International expected nearly 20,000 here in San Diego. Among the dozens of concurrent sessions each day of this four-day scramble, stem cells got one track on one day this year. But listening to the … Continue reading BIO International Panel Showed Stem Cell Science Poised to Make a Difference in Medical Practice Soon
BIO International Panel Showed Stem Cell Science Poised to Make a Difference in Medical Practice Soon
When the biotechnology trade association began holding annual conferences in 1993, they drew 1,400 to the first event. This year BIO International expected nearly 20,000 here in San Diego. Among the dozens of concurrent sessions each day of this four-day scramble, stem cells got one track on one day this year. But listening to the … Continue reading BIO International Panel Showed Stem Cell Science Poised to Make a Difference in Medical Practice Soon
Stem Cell Stories that Caught our Eye: Speeding Stroke Recovery, HIV Clinical Trial, New Method for Growing Heart Cells
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Transplanting cells to speed stroke recovery. Stroke remains one of the most common forms of death and disability, yet utilization of therapies that can break … Continue reading Stem Cell Stories that Caught our Eye: Speeding Stroke Recovery, HIV Clinical Trial, New Method for Growing Heart Cells
The Stem Cellar 