Clinical fellow Brian Shy talks with postdoctoral scholar Tori Yamamoto in the Marson Lab at Gladstone Institutes on June 8th, 2022. Photo courtesy Gladstone Institutes. For years scientists have been touting the potential of CRISPR, a gene editing tool that allows you to target a specific mutation and either cut it out or replace it … Continue reading A better, faster, more effective way to edit genes
Gladstone Institutes
How some brilliant research may have uncovered a potential therapy for Alzheimer’s
Dr. Nicole Koutsodendris, photo courtesy Gladstone Institutes In the world of scientific research, the people doing clinical trials tend to suck up all the oxygen in the room. They’re the stars, the ones who are bringing potential therapies to patients. However, there’s another group of researchers who toil away in the background, but who are … Continue reading How some brilliant research may have uncovered a potential therapy for Alzheimer’s
Newly-developed organoid mimics how gut and heart tissues arise cooperatively from stem cells
Gladstone Senior Investigator Todd McDevitt, PhD said this first-of-its-kind organoid could serve as a new tool for laboratory research and improve our understanding of how developing organs and tissues cooperate and instruct each other.
Creating a diverse group of future scientists
Students in CIRM's Bridges program showing posters of their work If you have read the headlines lately, you’ll know that the COVID-19 pandemic is having a huge impact on the shipping industry. Container vessels are forced to sit out at anchor for a week or more because there just aren’t enough dock workers to unload … Continue reading Creating a diverse group of future scientists
Heads or tails? Stem cells help guide the decision
Two cell embryo There are many unknown elements for what triggers the cells in an embryo to start dividing and multiplying and becoming every single cell in the body. Now researchers at the Gladstone Institutes in San Francisco have uncovered one of those elements, how embryos determine which cells become the head and which the … Continue reading Heads or tails? Stem cells help guide the decision
How stem cells play “follow the leader”
Todd McDevitt, PhD Photo courtesy: Gladstone Institutes It’s hard enough trying to follow the movements of individuals in a crowd of people, but imagine how much harder it is to follow the movements of stem cells crowded into a tiny petri dish. Well, researchers at the Gladstone Institutes in San Francisco have done just that. … Continue reading How stem cells play “follow the leader”
Persistence pays off in search for clue to heart defects
A team of scientists led by Benoit Bruneau (left), including Irfan Kathiriya (center) and Kavitha Rao (right), make inroads into understanding what genes are improperly deployed in some cases of congenital heart disease. Photo courtesy Gladstone Institute For more than 20 years Dr. Benoit Bruneau has been trying to identify the causes of congenital heart … Continue reading Persistence pays off in search for clue to heart defects
Gladstone scientists respond to coronavirus pandemic
In these uncertain times, we often look to our top scientists for answers as well as potential solutions. But where does one begin to try and solve a problem of this magnitude? The first logical step is building on the supplies currently available, the work already accomplished, and the knowledge acquired. This is the approach … Continue reading Gladstone scientists respond to coronavirus pandemic
When Google turns on you, you know you are in trouble
For years CIRM and others in the stem cell community (hello Paul Knoepfler) have been warning people about the dangers of going to clinics offering unproven and unapproved stem cell therapies. Recently the drum beat of people and organizations coming out in support of that stand has grown louder and louder. Mainstream media – TV … Continue reading When Google turns on you, you know you are in trouble
How stem cells know the right way to make a heart . And what goes wrong when they don’t
Gladstone scientists Deepak Srivastava (left), Yvanka De Soysa (center), and Casey Gifford (right) publish a complete catalog of the cells involved in heart development. The invention of GPS navigation systems has made finding your way around so much easier, providing simple instructions on how to get from point A to point B. Now, a new … Continue reading How stem cells know the right way to make a heart . And what goes wrong when they don’t
The Stem Cellar 