THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Ezra Cohen, photo courtesy UCSD Hematologic malignancies are cancers that affect the blood, bone marrow and lymph nodes and include different forms of leukemia and lymphoma. Current treatments can be effective, but in those patients that do not respond, there are few treatment options. Today, … Continue reading Stem Cell Agency Board Invests in Therapy Targeting Deadly Blood Cancers
colon cancer
Blocking pancreatic cancer stem cells
John Cashman Cancer stem cells are one of the main reasons why cancers are able to survive surgery, chemotherapy and radiation. They are able to hide from those therapies and, at a future date, emerge and spread the cancer in the body once again. Jionglia Cheng, PhD. Jionglia Cheng, PhD., the lead author of a … Continue reading Blocking pancreatic cancer stem cells
First patient treated for colon cancer using reprogrammed adult cells
Dr. Sandip Patel (left) and Dr. Dan Kaufman (center) of UC San Diego School of Medicine enjoy a light-hearted moment before Derek Ruff (right) receives the first treatment for cancer using human-induced pluripotent stem cells (hiPSCs). Photo courtesy of UC San Diego Health. For patients battling cancer for the first time, it can be quite … Continue reading First patient treated for colon cancer using reprogrammed adult cells
Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies
When the immune system comes up as a topic in everyday conversation, it’s usually related to fighting off a cold or flu. While our immune cells certainly do detect and neutralize invading bacteria and viruses, they also play a critical role in killing abnormal, cancerous cells from within our bodies. “Don’t Eat Me” Signal 101 … Continue reading Second “Don’t Eat Me” Signal Identified in Cancer Cells, Points to New Immunotherapies
CIRM-Funded Clinical Trials Targeting Cancers
Welcome to the Month of CIRM! As we mentioned in last Thursday’s blog, during the month of October we’ll be looking back at what CIRM has done since the agency was created by the people of California back in 2004. To start things off, we’ll be focusing on CIRM-funded clinical trials this week. Supporting clinical … Continue reading CIRM-Funded Clinical Trials Targeting Cancers
Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
Colon cancer is a global killer. Each year more than one million people worldwide are diagnosed with it; more than half a million die from it. If diagnosed early enough the standard treatment involves surgery, chemotherapy, radiation or targeted drug therapy to destroy the tumors. In many cases this may work. But in some cases, … Continue reading Protein that turns normal cells into cancer stem cells offers target to fight colon cancer
New Cellular Tracking Device Tests Ability of Cell-Based Therapies to Reach Intended Destination
Therapies aimed at replacing damaged cells with a fresh, healthy batch hold immense promise—but there remains one major sticking point: once you have injected new, healthy cells into the patient, how do you track them and how do you ensure they do the job for which they were designed? Unfortunately, there’s no easy solution. The … Continue reading New Cellular Tracking Device Tests Ability of Cell-Based Therapies to Reach Intended Destination
Stem Cell Stories that Caught our Eye: “Let it Grow” Goes Viral, Stroke Pilot Study, The Bowels of Human Stem Cells, Tumor ‘Safety Lock.’
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. “Let it Grow” Goes Viral (and National!): Last week on The Stem Cellar we shared one of our favorite student videos from our annual Creativity … Continue reading Stem Cell Stories that Caught our Eye: “Let it Grow” Goes Viral, Stroke Pilot Study, The Bowels of Human Stem Cells, Tumor ‘Safety Lock.’
Immune System “Double Agent” Fuels Colon Cancer Stem Cells, New Study Finds
Researchers have discovered that a type of cell normally tasked with defending the body against foreign invaders actually spurs the development of colon cancer stem cells. This discovery, published in the journal Immunity, offers new insight into why some forms of cancer come back again and again—even in the face of aggressive treatment. Led by … Continue reading Immune System “Double Agent” Fuels Colon Cancer Stem Cells, New Study Finds
The Stem Cellar 