Image description: T cell infected with HIV. Image Credit: National Institute of Allergy and Infectious Diseases (NIAID) In June of last year we wrote about how Dr. Scott Kitchen and his team at UCLA are engineering blood forming stem cells in order to fight HIV, a potentially deadly virus that attacks the immune system and … Continue reading CIRM funding helps improve immune cell therapy to combat HIV
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CIRM funding helps identify potential COVID-19 treatment
The steps of the virus growth cycle that can be targeted with therapies: The virus enters a host cell (1), the virus's genetic instructions are released, taking over cellular machinery (2), the virus is replicated within the cell (3) and copies of the virus exit the cell in search of new host cells to infect … Continue reading CIRM funding helps identify potential COVID-19 treatment
Newly designed “bioink” get us one step closer to 3D printed organs
3D bioprinted small airways made out of two cell types (blue and yellow) remain open over time. 3D printing technology has revolutionized the way we think about creating things with complex designs with the simple click of a button. The ability to be able to give a computer a specific set of instructions and hit … Continue reading Newly designed “bioink” get us one step closer to 3D printed organs
Study shows reduction in brain injury after stroke patients were treated with their own stem cells
Illustration showing the mechanism of an ischemic stroke. In an ischemic stroke, blood supply to part of the brain is decreased, leading to dysfunction of that area of the brain. Here, a blood clot is the reason for restricted blood flow. Stroke is the third leading cause of death and serious long-term disability and affects … Continue reading Study shows reduction in brain injury after stroke patients were treated with their own stem cells
A Match Made in Heaven, if heaven were in Oakland!
The Matchmaker - by Gerrit van Honthorst Throughout history, matchmakers have played an important role in bringing together couples for arranged marriages. Fast forward to today and CIRM is now playing a similar role. We’re not looking to get anyone hitched, what we are trying to do is create partnerships between people we are funding … Continue reading A Match Made in Heaven, if heaven were in Oakland!
Study shows connection between bipolar disorder and neuroinflammation
Astrocytes, which provide structural support and protection for neurons and also supply them with nutrients and oxygen. Bipolar disorder (BPD) is a mental disorder that causes unusual shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks. In the United States, recent research has shown that 1.6% of the population … Continue reading Study shows connection between bipolar disorder and neuroinflammation
A little history in the making by helping the tiniest patients
Dr. Diana Farmer stands with Dr. Aijun Wang and their UC Davis research team. It’s appropriate that at the start of Women’s History Month, UC Davis’ Dr. Diana Farmer is making a little history of her own. She launched the world’s first clinical trial using stem cells to treat spina bifida before the child is … Continue reading A little history in the making by helping the tiniest patients
Stem cell gene therapy for Fabry disease shows positive results in patients
Darren Bidulka rests after his modified blood stem cells were transplanted into him at the Foothills Medical Centre in Calgary in 2017, allowing him to stop his enzyme therapy. (From left): Dr. Jeffrey Medin, Medical College of Wisconsin, Dr. Aneal Khan, the experimental trial lead in Calgary, and Darren Bidulka. Image Credit: Darren Bidulka Fabry … Continue reading Stem cell gene therapy for Fabry disease shows positive results in patients
Scientists look at how the lung and brain respond differently to SARS-CoV-2 infection
UC San Diego School of Medicine researchers found approximately 10-fold higher SARS-CoV-2 infection (green) in lung organoids (left), compared to brain organoids (right). Image courtesy of UCSD Health Since the start of the coronavirus pandemic early last year, scientists all over the world are still trying to better understand SARS-CoV-2, the virus that causes COVID-19. … Continue reading Scientists look at how the lung and brain respond differently to SARS-CoV-2 infection
Scientists use stem cells to create Neanderthal-like “mini-brain”
Alysson R. Muotri, Ph.D. The evolution of modern day humans has always been a topic that has been shrouded in mystery. Some of what is known is that Neanderthals, an archaic human species that lived on this planet up until about 11,700 years ago, interbred with our species (Homo sapiens) at some point in time. … Continue reading Scientists use stem cells to create Neanderthal-like “mini-brain”
The Stem Cellar 