How the Tooth Fairy is helping unlock the secrets of autism

Our 2021-22 Annual Report is now online. It’s filled with information about the work we have done over the last year (we are on a fiscal calendar year from July 1 – June 30), the people who have helped us do that work, and some of the people who have benefited from that work. One … Continue reading How the Tooth Fairy is helping unlock the secrets of autism

Meet the man who is unlocking the secrets of autism and sending mini-brains into space

THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST Dr. Alysson Muotri, UC San Diego Normally if you meet someone who has a mini-fridge filled with brains, your first thought is to call the police. But when that someone is Dr. Alysson Muotri, a professor at U.C. San Diego, your second thought is “do tell … Continue reading Meet the man who is unlocking the secrets of autism and sending mini-brains into space

City of Hope scientists use stem cells to develop ‘mini-brains’ to study Alzheimer’s and to test drugs in development

Alzheimer's is a progressive disease that destroys memory and other important mental functions. According to the non-profit HFC, co-founded by CIRM Board member Lauren Miller Rogen and her husband Seth Rogen, more than 5 million Americans are living with Alzheimer's. It is the 6th leading cause of death in the U.S and it is estimated … Continue reading City of Hope scientists use stem cells to develop ‘mini-brains’ to study Alzheimer’s and to test drugs in development

Scientists use stem cell ‘mini-brains’ to better understand signs of frontotemporal dementia

Dementia is a general term that describes a set of diseases that impair the ability to remember, think, or make decisions that interfere with doing everyday activities. According to the World Health Organization (WHO), around 50 million people worldwide have dementia with nearly 10 million new cases every year. Although it primarily affects older people … Continue reading Scientists use stem cell ‘mini-brains’ to better understand signs of frontotemporal dementia

Scientists look at how the lung and brain respond differently to SARS-CoV-2 infection

UC San Diego School of Medicine researchers found approximately 10-fold higher SARS-CoV-2 infection (green) in lung organoids (left), compared to brain organoids (right). Image courtesy of UCSD Health Since the start of the coronavirus pandemic early last year, scientists all over the world are still trying to better understand SARS-CoV-2, the virus that causes COVID-19. … Continue reading Scientists look at how the lung and brain respond differently to SARS-CoV-2 infection

Scientists use stem cells to create Neanderthal-like “mini-brain”

Alysson R. Muotri, Ph.D. The evolution of modern day humans has always been a topic that has been shrouded in mystery. Some of what is known is that Neanderthals, an archaic human species that lived on this planet up until about 11,700 years ago, interbred with our species (Homo sapiens) at some point in time. … Continue reading Scientists use stem cells to create Neanderthal-like “mini-brain”

CIRM funded researchers discover link between Alzheimer’s gene and COVID-19

Dr. Yanhong Shi (left) and Dr. Vaithilingaraja Arumugaswami (right) All this month we are using our blog and social media to highlight a new chapter in CIRM’s life, thanks to the voters approving Proposition 14. We are looking back at what we have done since we were created in 2004, and also looking forward to the … Continue reading CIRM funded researchers discover link between Alzheimer’s gene and COVID-19

“Mini-brains” model an autism spectrum disorder and help test treatments

Alysson Muotri, PhD, professor and director of the Stem Cell Program at UC San Diego School of Medicine and member of the Sanford Consortium for Regenerative Medicine. Image credit: UC San Diego Health Rett syndrome is a rare form of autism spectrum disorder that impairs brain development and causes problems with movement, speech, and even … Continue reading “Mini-brains” model an autism spectrum disorder and help test treatments

Parkinson’s Disease and Stem Cells

Lila Collins, PhD A few weeks ago we held a Facebook Live "Ask the Stem Cell Team About Parkinson's Disease" event. As you can imagine we got lots of questions but, because of time constraints, only had time to answer a few. Thanks to my fabulous CIRM colleagues, Dr. Lila Collins and Dr. Kent Fitzgerald, … Continue reading Parkinson’s Disease and Stem Cells

Ask the Stem Cell Team About Autism

On March 19th we held a special Facebook Live "Ask the Stem Cell Team About Autism" event. We were fortunate enough to have two great experts - Dr. Alysson Muotri from UC San Diego, and CIRM's own Dr. Kelly Shepard. As always there is a lot of ground to cover in under one hour and … Continue reading Ask the Stem Cell Team About Autism