Three people left blind by Florida clinic’s unproven stem cell therapy

The report makes for chilling reading. Three women, all suffering from macular degeneration – the leading cause of vision loss in the US – went to a Florida clinic hoping that a stem cell therapy would save their eyesight. Instead, it caused all three to go blind. The study, in the latest issue of the … Continue reading Three people left blind by Florida clinic’s unproven stem cell therapy

California’s stem cell agency rounds up the year with two more big hits

It’s traditional to end the year with a look back at what you hoped to accomplish and an assessment of what you did. By that standard 2016 has been a pretty good year for us at CIRM. Yesterday our governing Board approved funding for two new clinical trials, one to help kidney transplant patients, the … Continue reading California’s stem cell agency rounds up the year with two more big hits

How stem cells are helping change the face of medicine, one pioneering patient at a time

One of the many great pleasures of my job is that I get to meet so many amazing people. I get to know the researchers who are changing the face of medicine, but even more extraordinary are the people who are helping them do it, the patients. Attacking Cancer It’s humbling to meet people like … Continue reading How stem cells are helping change the face of medicine, one pioneering patient at a time

CIRM-funded stem cell trial for retinitis pigmentosa makes progress

A CIRM-funded clinical trial for retinitis pigmentosa (RP), a degenerative eye disease that causes blindness, recently reached its next milestone and announced the completion of its patient enrollment for a phase I/IIa study testing a stem cell derived therapy. This is a major step forward in determining whether this approach is both safe and effective … Continue reading CIRM-funded stem cell trial for retinitis pigmentosa makes progress

Advancements in gene editing make blind rats see light

Gene editing is a rapidly advancing technology that scientists are using to manipulate the genomes of cells with precision and accuracy. Many of these experiments are being conducted on stem cells to genetic mutations in an attempt to find cures for various diseases like cancer, HIV and blindness. Speaking of blindness, researchers from the Salk Institute … Continue reading Advancements in gene editing make blind rats see light

A patient perspective on how stem cells could give a second vision to the blind

October is Blindness Awareness month. In honor of the patients who suffer from diseases of blindness and of the scientists and doctors who work tirelessly to develop treatments and cures for these diseases, we are featuring an interview with Kristin Macdonald, a woman who is challenged by Retinitis Pigmentosa (RP). RP is a genetically inherited … Continue reading A patient perspective on how stem cells could give a second vision to the blind

Trash talking and creating a stem cell community

Imilce Rodriguez-Fernandez likes to talk trash. No, really, she does. In her case it’s cellular trash, the kind that builds up in our cells and has to be removed to ensure the cells don’t become sick. Imilce was one of several stem cell researchers who took part in a couple of public events over the … Continue reading Trash talking and creating a stem cell community

Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see

“A pale hue”. For most of us that is a simple description, an observation about color. For Kristin Macdonald it’s a glimpse of the future. In some ways it’s a miracle. Kristin lost her sight to retinitis pigmentosa (RP). For many years she was virtually blind. But now, thanks to a clinical trial funded by … Continue reading Seeing is believing: how some scientists – including two funded by CIRM – are working to help the blind see

CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage

How retinitis pigmentosa erodes normal vision The failure rate for clinical trials is depressingly high. A study from Tufts University in 2010  found that for small molecules – the substances that make up more than 90 percent of the drugs on the market today – the odds of getting from a Phase 1 trial to … Continue reading CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage

Why is a cell therapy that restores sight to the blind against the law?

A lot of people are frustrated with the US Food and Drug Administration (FDA) and its woefully slow process for approving stem cell therapies. That’s one of the reasons why we started the CIRM Stem Cell Champions campaign, to gather as many like-minded supporters of stem cell research as possible and help to change the … Continue reading Why is a cell therapy that restores sight to the blind against the law?