This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Our Agency has funded a total of … Continue reading CIRM-Funded Clinical Trials Targeting Brain and Eye Disorders
Asterias Biotherapeutics
Stem cell stories that caught our eye: skin grafts fight diabetes, reprogramming the immune system, and Asterias expands spinal cord injury trial sites
Here are the stem cell stories that caught our eye this week. Skin grafts fight diabetes and obesity. An interesting new gene therapy strategy for fighting type 1 diabetes and obesity surfaced this week. Scientists from the University of Chicago made genetically engineered skin grafts that secrete a peptide hormone called glucagon-liked peptide-1 (GLP-1). This … Continue reading Stem cell stories that caught our eye: skin grafts fight diabetes, reprogramming the immune system, and Asterias expands spinal cord injury trial sites
CIRM-funded stem cell clinical trial for spinal cord injury expands patient recruitment
It’s always great to start the week off with some good news. Today we learned that the Food and Drug Administration (FDA) has given Asterias Biotherapeutics approval to expand the number and type of people with spinal cord injuries that it treats in their CIRM-funded clinical trial. Up till now, Asterias has been treating people … Continue reading CIRM-funded stem cell clinical trial for spinal cord injury expands patient recruitment
Positively good news from Asterias for CIRM-funded stem cell clinical trial for spinal cord injury
Whenever I give a talk on stem cells one of the questions I invariably get asked is “how do you know the cells are going where you want them to and doing what you want them to?” The answer is pretty simple: you look. That’s what Asterias Biotherapeutics did in their clinical trial to treat … Continue reading Positively good news from Asterias for CIRM-funded stem cell clinical trial for spinal cord injury
Stem cell stories that caught our eye: spinal cord injury trial keeps pace; SMART cells make cartilage and drugs
CIRM-funded spinal cord injury trial keeping a steady pace Taking an idea for a stem cell treatment and developing it into a Food and Drug Administration-approved cell therapy is like running the Boston Marathon because it requires incremental progress rather than a quick sprint. Asterias Biotherapeutics continues to keep a steady pace and to hit … Continue reading Stem cell stories that caught our eye: spinal cord injury trial keeps pace; SMART cells make cartilage and drugs
Scientists make stem cell-derived nerve cells damaged in spinal cord injury
The human spinal cord is an information highway that relays movement-related instructions from the brain to the rest of the body and sensory information from the body back to the brain. What keeps this highway flowing is a long tube of nerve cells and support cells bundled together within the spine. When the spinal cord … Continue reading Scientists make stem cell-derived nerve cells damaged in spinal cord injury
Good news from Asterias’ CIRM-funded spinal cord injury trial
This week in the stem cell field, all eyes are on Asterias Biotherapeutics, a California-based company that’s testing a stem cell based-therapy in a CIRM-funded clinical trial for spinal cord injury patients. The company launched its Phase 1/2a clinical trial back in 2014 with the goal of determining the safety of the therapy and the … Continue reading Good news from Asterias’ CIRM-funded spinal cord injury trial
First spinal cord injury trial patient gets maximum stem cell dose
There comes a pivotal point in every experiment where you say “ok, now we are going to see if this really works.” We may be at that point in the clinical trial we are funding to see if stem cells can help people with spinal cord injuries. Today Asterias Biotherapeutics announced they have given the … Continue reading First spinal cord injury trial patient gets maximum stem cell dose
Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial
Today we bring you more good news about a CIRM-funded clinical trial for spinal cord injury that’s received a lot of attention lately in the news. Asterias Biotherapeutics has treated its first patient in an expanded patient population of spinal cord injury patients who suffer from cervical, or neck, injuries. In late August, Asterias reported … Continue reading Full Steam Ahead: First Patient is Dosed in Expanded CIRM Spinal Cord Injury Trial
Asterias’ stem cell clinical trial shows encouraging results for spinal cord injury patients
When researchers are carrying out a clinical trial they have two goals: first, show that it is safe (the old “do no harm” maxim) and second, show it works. One without the other doesn’t do anyone any good in the long run. A few weeks ago Asterias Biotherapeutics showed that their CIRM-funded stem cell therapy … Continue reading Asterias’ stem cell clinical trial shows encouraging results for spinal cord injury patients