Senior author of the study Clive Svendsen, PhD (center) With funding support from the California Institute for Regenerative Medicine (CIRM), Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially protect diseased motor neurons … Continue reading CIRM-funded stem cell-gene therapy shows promise in ALS safety trial
Amyotrophic lateral sclerosis
Joining the movement to fight rare diseases
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST It’s hard to think of something as being rare when it affects up to 30 million Americans and 300 million people worldwide. But the truth is there are more than 6,000 conditions – those affecting 200,000 people or fewer – that are considered rare. Today, … Continue reading Joining the movement to fight rare diseases
A step forward in finding a treatment for a deadly neurological disorder
THIS BLOG IS ALSO AVAILABLE AS AN AUDIO CAST MRI section of a brain affected by ALS with the front section of the brain highlighted Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a nasty disease that steadily attacks nerve cells in the brain and spinal cord. It’s pretty much always fatal … Continue reading A step forward in finding a treatment for a deadly neurological disorder
CIRM Board Approves New Clinical Trial for ALS
This past Friday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $11.99 million to Cedars-Sinai to fund a clinical trial for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a neurodegenerative disease that results in the death of nerve cells in the brain and spinal cord, causing … Continue reading CIRM Board Approves New Clinical Trial for ALS
CIRM supported study of gene silencer blocks ALS degeneration, saves motor function
Dr. Martin Marsala, UC San Diego Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease, is a neurodegenerative disease that destroys the nerve cells in the brain and spinal cord. As a result of ALS, the motor neurons that enable bodily movement and muscle control are harmed, which can make it difficult to move, … Continue reading CIRM supported study of gene silencer blocks ALS degeneration, saves motor function
Stem cell model reveals deeper understanding into “ALS resilient” neurons
A descriptive illustration of Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease. Courtesy of ALS Foundation website. Understanding the basic biology of how a cell functions can be crucial to being able to better understand a disease and unlock a potential approach for a treatment. Stem cells are unique in that they give … Continue reading Stem cell model reveals deeper understanding into “ALS resilient” neurons
A stepping stone for bringing stem cell therapy to patients with ALS
Imagine being told that you have a condition that gradually causes you to lose the ability to control your body movements, from picking up a pencil to walking to even breathing. Such is the reality for the nearly 6,000 people who are diagnosed with amyotrophic lateral sclerosis (ALS) every year, in the United States alone. … Continue reading A stepping stone for bringing stem cell therapy to patients with ALS
ALS is in the spotlight in CIRM’s “Ask the Expert About ALS & Stem Cells” Facebook Live event
American Football great Dwight Clark was renowned for having the safest hands in the game when he played for the San Francisco 49ers. But in September 2015 he was diagnosed with ALS (also known as Lou Gehrig’s disease) after not being able to use those hands to open a package of sugar. Less than three … Continue reading ALS is in the spotlight in CIRM’s “Ask the Expert About ALS & Stem Cells” Facebook Live event
Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is one of those conditions that a lot of people know about but don’t know a lot about. If they are fortunate it will stay that way. ALS is a nasty neurodegenerative disease that attacks motor neurons, the cells in the brain and spinal cord … Continue reading Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease
CIRM-Funded Clinical Trials Targeting Brain and Eye Disorders
This blog is part of our Month of CIRM series, which features our Agency’s progress towards achieving our mission to accelerate stem cell treatments to patients with unmet medical needs. This week, we’re highlighting CIRM-funded clinical trials to address the growing interest in our rapidly expanding clinical portfolio. Our Agency has funded a total of … Continue reading CIRM-Funded Clinical Trials Targeting Brain and Eye Disorders
The Stem Cellar 