CIRM invests in stem cell clinical trial targeting lung cancer and promising research into osteoporosis and incontinence

The five-year survival rate for people diagnosed with the most advanced stage of non-small cell lung cancer (NSCLC) is pretty grim, only between one and 10 percent. To address this devastating condition, the Board of the California Institute for Regenerative Medicine (CIRM) today voted to invest almost $12 million in a team from UCLA that … Continue reading CIRM invests in stem cell clinical trial targeting lung cancer and promising research into osteoporosis and incontinence

Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is one of those conditions that a lot of people know about but don’t know a lot about. If they are fortunate it will stay that way. ALS is a nasty neurodegenerative disease that attacks motor neurons, the cells in the brain and spinal cord … Continue reading Boosting immune system cells could offer a new approach to treating Lou Gehrig’s disease

The Mother of Modern Medicine: Henrietta Lacks’ Portrait Unveiled at National Portrait Gallery

Back during my research scientist days, using HeLa cells for my experiments was as commonplace as a carpenter reaching for his hammer at a construction site. What makes these cells so handy is their robustness: they are easy to maintain in the lab where they divide indefinitely in petri dishes. Henrietta Lacks and the Story … Continue reading The Mother of Modern Medicine: Henrietta Lacks’ Portrait Unveiled at National Portrait Gallery

New findings about muscle stem cells reveals the potential for growing replacement organs

Chrissa Kioussi’s group at Oregon State University has made exciting advances in further unraveling the scientific mysteries of stem cells. In work detailed in Scientific Reports, this group found that muscle-specific stem cells actually have the ability to make multiple different cell types. Initially, this group was interested in understanding how gene expression changes during … Continue reading New findings about muscle stem cells reveals the potential for growing replacement organs

Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease

Triple negative breast cancer is more aggressive and difficult to treat than other forms of the disease and, as a result, is more likely to spread throughout the body and to recur after treatment. Now a team at the University of Southern California have identified a protein that could help change that. The research, published … Continue reading Stem Cell Roundup: Protein shows promise in treating deadliest form of breast cancer: mosquito spit primes our body for disease

A scalable, clinic-friendly recipe for converting skin cells to muscle cells

Way back in 1987, about two decades before Shinya Yamanaka would go on to identify four proteins that can reprogram skin cells into induced pluripotent stem cells (iPSCs), Harold Weintraub’s lab identified the first “master control” protein, MyoD, which can directly convert a skin cell into a muscle cell. Though MyoD opened up new approaches … Continue reading A scalable, clinic-friendly recipe for converting skin cells to muscle cells

Using biological “codes” to generate neurons in a dish

Investigators at the Scripps Research Institute are making brain waves in the field of neuroscience. Until now, neuroscience research has largely relied on a variety of animal models to understand the complexities of various brain or neuronal diseases. While beneficial for many reasons, animal models do not always allow scientists to understand the precise mechanism … Continue reading Using biological “codes” to generate neurons in a dish

Breaking down barriers to advance stem cell therapies – the view from the Vatican conference

All hands were on deck at the “Unite to Cure” conference, organized by the Cura Foundation and the Vatican Pontifical Council,  and held at the Vatican on April 26-28. Religious leaders, scientists, physicians, philanthropists, industry leaders, government, academic leaders and members of the entertainment industry gathered to discuss how to improve human health and to … Continue reading Breaking down barriers to advance stem cell therapies – the view from the Vatican conference

TELL ME WHAT I NEED TO KNOW: A Patient Advocate’s guide to being a Patient Advocate

A few weeks ago I was at the CIRM Alpha Stem Cell Clinic Network Symposium at UCLA and was fortunate enough to hear Gianna McMillan speak about patient advocacy. It was a powerful, moving, funny, and truly engaging talk. I quickly realized I wanted to blog about her talk and so for the first few … Continue reading TELL ME WHAT I NEED TO KNOW: A Patient Advocate’s guide to being a Patient Advocate

CIRM applauds FDA crackdown on stem cell clinics that “peddle unapproved treatments.”

CIRM is commending the US Food and Drug Administration (FDA) for its action against two stem cell clinics offering unapproved therapies. On Wednesday, the FDA filed two complaints in federal court seeking a permanent injunction against California Stem Cell Treatment Center Inc. and US Stem Cell Clinic LLC. of Sunrise, Florida. The FDA says the … Continue reading CIRM applauds FDA crackdown on stem cell clinics that “peddle unapproved treatments.”