Mending Stem Cells: The Past, Present & Future of Regenerative Medicine

UCSF's Mission Bay Campus For years we have talked about the “promise” and the “potential” of stem cells to cure patients. But more and more we are seeing firsthand how stem cells can change a patient’s life, even saving it in some cases. That’s the theme of the 4th Annual CIRM Alpha Stem Cell Clinics … Continue reading Mending Stem Cells: The Past, Present & Future of Regenerative Medicine

CRISPR-Cas9 101: an overview and the role it plays in developing therapies

Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies

Promising start to CIRM-funded trial for life-threatening blood disorder

Aristotle At CIRM we are always happy to highlight success stories, particularly when they involve research we are funding. But we are also mindful of the need not to overstate a finding. To quote the Greek philosopher Aristotle (who doesn’t often make an appearance on this blog), “one swallow does not a summer make”. In … Continue reading Promising start to CIRM-funded trial for life-threatening blood disorder

New model unlocks clues to treating deadly childhood cancer

CIRM-funded research at Sanford Burnham Prebys Medical Discovery Institute in San Diego is identifying compounds that could be used to help children battling a deadly brain cancer. The cancer is choroid plexus carcinoma (CPC), a rare brain tumor that occurs mainly in children. As it grows the tumor can affect nearby parts of the brain … Continue reading New model unlocks clues to treating deadly childhood cancer

Old cells need not apply: how a stem cell’s age can impact potential treatments

Getting older is a normal, at times existential, part of life. The outward changes are abundant and noticeable: thinning of the hair, greying of the hair, and added lines to the face. There are also changes that happen that are not so abundantly clear in terms of outward appearance: slowing of healing time for bone … Continue reading Old cells need not apply: how a stem cell’s age can impact potential treatments

Targeting clinics offering bogus stem cell therapies

For some years now CIRM has been raising the alarm about the growing numbers of clinics offering unproven and unapproved stem cell therapies. But we are not alone. Now a leader of the California state Assembly is taking action, trying to ensure the clinics follow the law and don’t endanger patients. Kevin Mullin is the … Continue reading Targeting clinics offering bogus stem cell therapies

Organoids revolutionize approach to studying a variety of diseases

Organoids There are limitations to studying cells under a microscope. To understand some of the more complex processes, it is critical to see how these cells behave in an environment that is similar to conditions in the body. The production of organoids has revolutionized this approach. Organoids are three-dimensional structures derived from stem cells that … Continue reading Organoids revolutionize approach to studying a variety of diseases

Stem Cell Agency Awards Almost $4 Million to Develop a Treatment for Spinal Degeneration

Today the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $3.9 million to Ankasa Regenerative Therapeutics for a promising approach to treat a degenerative condition that can cause chronic, progressive back pain. As we get older, the bones, joints and ligaments in our back become weak and less able to hold the … Continue reading Stem Cell Agency Awards Almost $4 Million to Develop a Treatment for Spinal Degeneration

Rats, research and the road to new therapies

Don Reed Don Reed has been a champion of CIRM even before there was a CIRM. He's a pioneer in pushing for funding for stem cell research and now he's working hard to raise awareness about the difference that funding is making. In a recent article on Daily Kos, Don highlighted one of the less … Continue reading Rats, research and the road to new therapies

Newly developed biosensor can target leukemic stem cells

Dr. Michael Milyavsky (left) and his research student Muhammad Yassin (right). Image courtesy of Tel Aviv University. Every three minutes, one person in the United States is diagnosed with a blood cancer, which amounts to over 175,000 people every year. Every nine minutes, one person in the United States dies from a blood cancer, which … Continue reading Newly developed biosensor can target leukemic stem cells