The human genome Way back in the 1990’s scientists were hard at work decoding the human genome, trying to map and understand all the genes that make up people. At the time there was a sense of hope, a feeling that once we had decoded the genome, we’d have cures for all sorts of things … Continue reading Time and money and advancing stem cell research
Next generation of stem cell scientists leave their mark
One of the favorite events of the year for the team here at CIRM is our annual SPARK (Summer Program to Accelerate Regenerative Medicine Knowledge) conference. This is where high school students, who spent the summer interning at world class stem cell research facilities around California, get to show what they learned. It’s always an … Continue reading Next generation of stem cell scientists leave their mark
Boosting the blood system after life-saving therapy
Following radiation, the bone marrow shows nearly complete loss of blood cells in mice (left). Mice treated with the PTP-sigma inhibitor displayed rapid recovery of blood cells (purple, right): Photo Courtesy UCLA Chemotherapy and radiation are two of the front-line weapons in treating cancer. They can be effective, even life-saving, but they can also be … Continue reading Boosting the blood system after life-saving therapy
Drug used to treat multiple sclerosis may improve glioblastoma outcomes
Dr. Jeremy Rich, UC San Diego Glioblastoma is an aggressive form of cancer that invades brain tissue, making it extremely difficult to treat. Current therapies involving radiation and chemotherapy are effective in destroying the bulk of brain cancer cells, but they are not able to reach the brain cancer stem cells, which have the ability … Continue reading Drug used to treat multiple sclerosis may improve glioblastoma outcomes
Stem cell progress and promise in fighting leukemia
Computer illustration of a cancerous white blood cell in leukemia. There is nothing you can do to prevent or reduce your risk of leukemia. That’s not a very reassuring statement considering that this year alone almost 62,000 Americans will be diagnosed with leukemia; almost 23,000 will die from the disease. That’s why CIRM is funding … Continue reading Stem cell progress and promise in fighting leukemia
CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Dr. Mathew Blurton-Jones, leader of team that developed the chimeric "Mighty Mouse" model at the University of California, Irvine In ancient Greek mythology, a Chimera was a creature that was usually depicted as a lion with an additional goat head and a serpent for a tail. Due to the Chimera's animal hybrid nature, the term … Continue reading CIRM-Funded Researchers Develop Chimeric “Mighty Mouse” Model to Study Alzheimer’s Disease
Newly discovered “don’t eat me” signal shows potential for ovarian and triple-negative breast cancer treatment
Stanford researchers have found that cancer cells have a protein called CD24 on their surface that enables them to protect themselves against the body's immune cells. Courtesy of Shutterstock Getting a breast cancer diagnosis is devastating news in and of itself. Currently, there are treatment options that target three different types of receptors, which are … Continue reading Newly discovered “don’t eat me” signal shows potential for ovarian and triple-negative breast cancer treatment
One family’s fight to save their son’s life, and how stem cells made it possible
CIRM's mission is very simple: to accelerate stem cell treatments to patients with unmet medical needs. Anne Klein's son, Everett, was a poster boy for that statement. Born with a fatal immune disorder Everett faced a bleak future. But Anne and husband Brian were not about to give up. The following story is one Anne … Continue reading One family’s fight to save their son’s life, and how stem cells made it possible
How stem cells know the right way to make a heart . And what goes wrong when they don’t
Gladstone scientists Deepak Srivastava (left), Yvanka De Soysa (center), and Casey Gifford (right) publish a complete catalog of the cells involved in heart development. The invention of GPS navigation systems has made finding your way around so much easier, providing simple instructions on how to get from point A to point B. Now, a new … Continue reading How stem cells know the right way to make a heart . And what goes wrong when they don’t
CIRM Board Approves $19.7 Million in Awards for Translational Research Program
In addition to approving funding for breast cancer related brain metastases last week, the CIRM Board also approved an additional $19.7 million geared towards our translational research program. The goal of this program is to help promising projects complete the testing needed to begin talking to the US Food and Drug Administration (FDA) about holding … Continue reading CIRM Board Approves $19.7 Million in Awards for Translational Research Program