Photo Courtesy of Andrea Fernandez de Soto Imagine a life where every time you step outside, everything in your environment poses a life-threatening risk. For children born with ADA-SCID (adenosine deaminase severe combined immunodeficiency), this is a reality. Their immune systems are so compromised that a common cold or a simple scrape on the knee … Continue reading Gene Therapy Brings Hope to Families Affected by Rare Immune Disorder
Stem cells
Two CIRM-funded research projects receive RMAT designation from FDA
The U.S. Food and Drug Administration (FDA) has granted Regenerative Medicine Advanced Therapy (RMAT) designation to two research projects funded by the California Institute for Regenerative Medicine (CIRM). RMAT is a fast-track designation that can help speed up the development, review, and potential approval of treatments for serious or life-threatening diseases. The first RMAT designation … Continue reading Two CIRM-funded research projects receive RMAT designation from FDA
Stem Cell Awareness: What are stem cells and why research is important
Have you heard of stem cells but don't know what they are or why they are essential in medical research? In celebration of Stem Cell Awareness Day, the second Wednesday in October that is dedicated to educating about the importance of stem cells, the California Institute for Regenerative Medicine (CIRM) is providing this guide on … Continue reading Stem Cell Awareness: What are stem cells and why research is important
From Undergraduate to Hero: Solano Student’s Life-Saving Bone Marrow Match Begins with One Swab
SCC student and CIRM trainee Jose Solorio donated bone marrow to save an 11-year-old patient's life in New York. In a remarkable display of compassion and scientific collaboration, Solano Community College (SCC) student Jose Solorio, a scholar in the college's biomanufacturing bachelor's program, has become a real-life hero. Through Solano’s partnership with the National Marrow … Continue reading From Undergraduate to Hero: Solano Student’s Life-Saving Bone Marrow Match Begins with One Swab
Supporting a CAR-T cell trial for kidney cancer
Photo Credit: Allogene Therapeutics. Image of the ALLO-316 allogeneic CAR-T cell therapy. The California Institute for Regenerative Medicine (CIRM) awarded $15 million to Dr. John Le Gall and his team at Allogene Therapeutics. This funding will support the development of ALLO-316, an innovative anti-CD70 CAR-T cell product designed to treat metastatic clear cell renal cell … Continue reading Supporting a CAR-T cell trial for kidney cancer
CIRM’s $31 million boost for cancer and eye disease research
The California Institute for Regenerative Medicine (CIRM) recently approved nearly $31 million in funding, further cementing our commitment to advancing the field of regenerative medicine. This substantial investment aims to drive clinical research targeting various cancers and eye diseases. CIRM’s dedication to fostering innovative treatments is demonstrated through its clinical program, which funds eligible stem … Continue reading CIRM’s $31 million boost for cancer and eye disease research
CIRM invests $1.5 million to UCLA for research identifying risk factors for viral infections
Image of Michael Wells, PhD from UCLA The California Institute for Regenerative Medicine (CIRM) recently awarded $1.5 million to a new research project led by Michael Wells, PhD, of UCLA, that aims to identify the genetic and molecular risk factors underlying disease-causing viral infections in multiple diverse ancestral populations. Dr. Wells and his team of … Continue reading CIRM invests $1.5 million to UCLA for research identifying risk factors for viral infections
Update on spinal cord injury patient enrolled in CIRM-funded stem cell clinical trial
Jake Javier and his parents at Duke University A spinal cord injury (SCI) is devastating, changing a person’s life in an instant. Every year, around the world, between 250,000 and 500,000 people suffer a spinal cord injury. Most of these are caused by trauma to the spinal column, thereby affecting the spinal cord's ability to … Continue reading Update on spinal cord injury patient enrolled in CIRM-funded stem cell clinical trial
Bubble baby treatment cleared to restart clinical trial
Evie Vaccaro: Photo courtesy Nancy Ramos Three families battling a life-threatening immune disorder got some great news last week. A clinical trial that could save the life of their child has once again been given the go-ahead by the US Food and Drug Administration (FDA). The clinical trial is the work of UCLA’s Dr. Don … Continue reading Bubble baby treatment cleared to restart clinical trial
Making transplants easier for kids, and charting a new approach to fighting solid tumors.
Every year California performs around 100 kidney transplants in children but, on average, around 50 of these patients will have their body reject the transplant. These children then have to undergo regular dialysis while waiting for a new organ. Even the successful transplants require a lifetime of immunosuppression medications. These medications can prevent rejection but … Continue reading Making transplants easier for kids, and charting a new approach to fighting solid tumors.
The Stem Cellar 