A recent study estimated there may be more than 500 million people worldwide who have diabetes. That’s an astounding figure and makes diabetes one of the largest chronic disease epidemics in human history. One of the most serious consequences of untreated or uncontrolled diabetes is kidney damage. That can lead to fatigue, weakness, confusion, kidney … Continue reading CIRM Board targets diabetes and kidney disease with big stem cell research awards
Research News
CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage
How retinitis pigmentosa erodes normal vision The failure rate for clinical trials is depressingly high. A study from Tufts University in 2010 found that for small molecules – the substances that make up more than 90 percent of the drugs on the market today – the odds of getting from a Phase 1 trial to … Continue reading CIRM-funded stem cell clinical trial for retinitis pigmentosa focuses on next stage
Salk Scientists Unlock New Secrets of Autism Using Human Stem Cells
Autism is a complex neurodevelopmental disorder whose mental, physical, social and emotional symptoms are highly variable from person to person. Because individuals exhibit different combinations and severities of symptoms, the concept of autism spectrum disorder (ASD) is now used to define the range of conditions. There are many hypotheses for why autism occurs in humans … Continue reading Salk Scientists Unlock New Secrets of Autism Using Human Stem Cells
The Spanish Inquisition and a tale of two stem cell agencies
Monty Python's Spanish Inquisition sketch: Photo courtesy Daily Mail UK It’s not often an article on stem cell research brings the old, but still much loved, British comedy series Monty Python into the discussion but a new study in the journal Cell Stem Cell does just that, comparing the impact of CIRM and the UK’s … Continue reading The Spanish Inquisition and a tale of two stem cell agencies
Scientists find new stem cell target for regenerating aging muscles
Today I’m going to use our former governor Arnold Schwarzenegger as an example of what happens to our muscles when we age. One of Arnold’s many talents when he was younger was being a professional bodybuilder. As you can see in this photo, Arnold worked hard to generate an impressive amount of muscle that landed … Continue reading Scientists find new stem cell target for regenerating aging muscles
T cell fate and future immunotherapies rely on a tag team of genetic switches
Imagine if scientists could build microscopic smart missiles that specifically seek out and destroy deadly, hard-to-treat cancer cells in a patient’s body? Well, you don’t have to imagine it actually. With techniques such as chimeric antigen receptor (CAR) T therapy, a patient’s own T cells – immune system cells that fight off viruses and cancer … Continue reading T cell fate and future immunotherapies rely on a tag team of genetic switches
From flies to mice: Improving stem cell therapy for degenerative eye diseases
Stem cell therapies for degenerative eye diseases sound promising – inject retinal progenitor cells derived from human pluripotent stem cells into the eye where they will integrate and replace damaged retinal tissue to hopefully restore sight. However, a significant road block is preventing these stem cell transplants from doing their job: the transplanted cells are … Continue reading From flies to mice: Improving stem cell therapy for degenerative eye diseases
BIO 2016: IMAGINE Curing Disease and Saving Lives Part 2
As promised, here is Part 2 of our blog coverage on the BIO International Convention currently ongoing in San Francisco. Here are a few more insights on the talks we attended and highlights of other coverage from top biotech journalists and media outlets. Keynote with Dr. Bennet Omalu and Will Smith on “Concussion” If you … Continue reading BIO 2016: IMAGINE Curing Disease and Saving Lives Part 2
IMAGINE Curing Disease and Saving Lives: BIO 2016 Part 1
Did you hear that? It’s the sound of more than 15,000 people taking a collective breath. That’s because we are now at the halfway point of the 2016 BIO International Convention, the world’s largest biotechnology gathering with over 900 speakers, 180 company presentations, 19 education tracks, 6 super sessions, and 35,000 partnering meetings. Now that’s … Continue reading IMAGINE Curing Disease and Saving Lives: BIO 2016 Part 1
Adding new stem cell tools to the Parkinson’s disease toolbox
Understanding a complicated neurodegenerative disorder like Parkinson’s disease (PD) is no easy task. While there are known genetic risk factors that cause PD, only about 10 percent of cases are linked to a genetic cause. The majority of patients suffer from the sporadic form of PD, where the causes are unknown but thought to be … Continue reading Adding new stem cell tools to the Parkinson’s disease toolbox
The Stem Cellar 