It seems like an oxymoron but one in ten Americans has a rare disease. With more than 7,000 known rare diseases it’s easy to see how each one could affect thousands of individuals and still be considered a rare or orphan condition. Only 5% of rare diseases have FDA approved therapies People with rare … Continue reading Rare disease underdogs come out on top at CIRM Board meeting
CIRM News
CIRM Alpha Stem Cell Clinics: Paving a Path to Cures
Our mission at CIRM is to accelerate stem cell treatments to patients with unmet medical needs. Over the past ten years, our agency has been tasked with carefully distributing $3 billion dollars of California state tax payer money to the best and brightest scientists in California (and outside too, providing they meet certain requirements). These … Continue reading CIRM Alpha Stem Cell Clinics: Paving a Path to Cures
Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
Your brain is made up of approximately 100 billion neurons. These are the cells that process information and pass along electrical and chemical signals to their other neuron buddies throughout the body to coordinate thoughts, movement, and many other functions. It’s no small task to create the intricate neuronal network that is the backbone of … Continue reading Unlocking the brain’s secrets: scientists find over 100 unique mutations in brain cells
Scientists use human stem cell models to target deadly brain cancer
Malignant brain cancer is a devastating disease and it’s estimated that more than 16,000 patients will die of it this year. One of the most aggressive forms of brain cancer is gliomas, which originate from the support cells in the brain or spine that keep nerve cells happy and functioning. Unfortunately, there is no cure … Continue reading Scientists use human stem cell models to target deadly brain cancer
Growing Stem Cell Research in California (Video)
How a Gladstone scientist is using bioengineering to push the pace of stem cell research At CIRM, we strive to fund the most promising stem cell research and speed the advancement of stem cell treatments to patients who need them. Because we are a state agency, we generally focus on funding scientists, universities, and companies … Continue reading Growing Stem Cell Research in California (Video)
CIRM-funded study suggests methods to make pluripotent stem cells are safe
We live in an era where stem cell treatments are already being tested in human clinical trials for eye disease, spinal cord injury, and type 1 diabetes. The hope is that transplanting stem cells or their cell derivatives will replace diseased tissue, restore function, and cure patients – all while being safe and without causing … Continue reading CIRM-funded study suggests methods to make pluripotent stem cells are safe
Family ties help drive UCLA’s search for a stem cell treatment for Duchenne muscular dystrophy
April Pyle, Courtney Young and Melissa Spencer: Photo courtesy UCLA Broad Stem Cell Research Center People get into science for all sorts of different reasons. For Courtney Young the reason was easy; she has a cousin with Duchenne muscular dystrophy. Now her work as part of a team at UCLA has led to a new … Continue reading Family ties help drive UCLA’s search for a stem cell treatment for Duchenne muscular dystrophy
How you derive embryonic stem cells matters
A scientist named James Thompson was the first to successfully culture human embryonic stem cells in 1998. He didn’t know it then, but his technique isolated a specific type of embryonic stem cell (ESC) that had a “primed pluripotent state”. There are actually two phases of pluripotency: naïve and primed. Naïve ESCs occur a step … Continue reading How you derive embryonic stem cells matters
A Tale of Two Stem Cell Treatments for Growing New Bones
Got Milk? If you grew up during the 90’s, you most certainly will remember the famous “Got Milk?” advertising campaign to boost milk consumption. The plug was that milk was an invaluable source of calcium, a mineral that’s essential for growing strong bones. Drinking three glasses of the white stuff a day, supposedly would help … Continue reading A Tale of Two Stem Cell Treatments for Growing New Bones
CREATE-ing tools that deliver genes past the blood-brain barrier
Your brain has a natural defense that protects it from infection and harm, it’s called the blood-brain barrier (BBB). The BBB is a selectively permeable layer of tightly packed cells that separates the blood in your circulatory system from your brain. Only certain nutrients, hormones, and molecules can pass through the BBB into the brain, … Continue reading CREATE-ing tools that deliver genes past the blood-brain barrier
The Stem Cellar 