Welcome back to our “Throwback Thursday” series on the Stem Cellar. Over the years, we’ve accumulated an arsenal of exciting stem cell stories about advances towards stem cell-based cures for serious diseases. This month we’re featuring stories about CIRM-funded clinical trials for blindness. 2017 has been an exciting year for two CIRM-funded clinical trials that … Continue reading Throwback Thursday: Progress to a Cure for Diseases of Blindness
CIRM funded research
Latest space launch sends mice to test bone-building drug
Astronauts on the International Space Station (ISS) received some furry guests this weekend with the launch of SpaceX’s Dragon supply capsule. On Saturday June 3rd, 40 mice were sent to the ISS along with other research experiments and medical equipment. Scientists will be treating the mice with a bone-building drug in search of a new … Continue reading Latest space launch sends mice to test bone-building drug
Stanford scientists devise an algorithm that identifies gene pairs associated with cancer
Using data from human tumor samples, Stanford scientists have developed a new computer algorithm to identify pairs of genes that cause cancer. Their research aims to identify alternative ways to target cancer-causing mutations that have thus far evaded effective clinical treatment. The study, which was published this week in Nature Communications, was led by senior … Continue reading Stanford scientists devise an algorithm that identifies gene pairs associated with cancer
“A limitless future”: young crash victim regains hand, finger movement after CIRM-funded trial
Back in March, we reported on Asterias Biotherapeutics’ exciting press release stating that its CIRM-funded stem cell-based therapy for spinal cord injury had shown improvement in six out of the six clinical trial patients receiving a ten million cell dose. What’s even more exciting is hearing stories about the positive impact of that data on … Continue reading “A limitless future”: young crash victim regains hand, finger movement after CIRM-funded trial
ViaCyte Advances Cell Replacement Therapy for High Risk Type 1 Diabetes
San Diego regenerative medicine company ViaCyte announced this week that the Food and Drug Administration (FDA) approved their Investigational New Drug (IND) Application for PEC-Direct, a cell-based therapy to treat patients at risk for severe complications caused by type 1 diabetes. In the US, IND approval is the final regulatory step required before a therapy … Continue reading ViaCyte Advances Cell Replacement Therapy for High Risk Type 1 Diabetes
Stem cell-derived blood-brain barrier gives more complete picture of Huntington’s disease
Like a sophisticated security fence, our bodies have evolved a barrier that protects the brain from potentially harmful substances in the blood but still allows the entry of essential molecules like blood sugar and oxygen. Just like in other parts of the body, the blood vessels and capillaries in the brain are lined with endothelial … Continue reading Stem cell-derived blood-brain barrier gives more complete picture of Huntington’s disease
Bridging the Gap: Regenerating Injured Bones with Stem Cells and Gene Therapy
Scientists from Cedars-Sinai Medical Center have developed a new stem cell-based technology in animals that mends broken bones that can’t regenerate on their own. Their research was published today in the journal Science Translational Medicine and was funded in part by a CIRM Early Translational Award. Over two million bone grafts are conducted every year … Continue reading Bridging the Gap: Regenerating Injured Bones with Stem Cells and Gene Therapy
UCSD scientists devise tiny sensors that detect forces at cellular level
A big focus of stem cell research is trying to figure how to make a stem cell specialize, or differentiate, into a desired cell type like muscle, liver or bone. When we write about these efforts in the Stem Cellar, it’s usually in terms of researchers identifying proteins that bind to a stem cell’s surface … Continue reading UCSD scientists devise tiny sensors that detect forces at cellular level
Positively good news from Asterias for CIRM-funded stem cell clinical trial for spinal cord injury
Whenever I give a talk on stem cells one of the questions I invariably get asked is “how do you know the cells are going where you want them to and doing what you want them to?” The answer is pretty simple: you look. That’s what Asterias Biotherapeutics did in their clinical trial to treat … Continue reading Positively good news from Asterias for CIRM-funded stem cell clinical trial for spinal cord injury
Stem cell stories that caught our eye: update on Capricor’s heart attack trial; lithium on the brain; and how stem cells do math
Today our partners Capricor Therapeutics announced that its stem cell therapy for patients who have experienced a large heart attack is unlikely to meet one of its key goals, namely reducing the scar size in the heart 12 months after treatment. The news came after analyzing results from patients at the halfway point of the … Continue reading Stem cell stories that caught our eye: update on Capricor’s heart attack trial; lithium on the brain; and how stem cells do math
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