We live in an era where stem cell treatments are already being tested in human clinical trials for eye disease, spinal cord injury, and type 1 diabetes. The hope is that transplanting stem cells or their cell derivatives will replace diseased tissue, restore function, and cure patients – all while being safe and without causing … Continue reading CIRM-funded study suggests methods to make pluripotent stem cells are safe
Genomics
CIRM-funded team traces molecular basis for differences between human and chimp face
So similar yet so different Whenever I go to the zoo, I could easily spend my entire visit hanging out with our not-so-distant relatives, the chimpanzees. To say we humans are similar to them is quite an understatement. Sharing 96% of our DNA, chimps are more closely related to us than they are to gorillas. And … Continue reading CIRM-funded team traces molecular basis for differences between human and chimp face
Throwback Thursday: Progress to a Cure for ALS
Welcome to our new “Throwback Thursday” (TBT) series. CIRM’s Stem Cellar blog has a rich archive of stem cell content that is too valuable to let dust bunnies take over. So we decided to brush off some of our older, juicy stories and see what advancements in stem cell research science have been made since! … Continue reading Throwback Thursday: Progress to a Cure for ALS
One-Time, Lasting Treatment for Sickle Cell Disease May be on Horizon, According to New CIRM-Funded Study
For the nearly 1,000 babies born each year in the United States with sickle cell disease, a painful and arduous road awaits them. The only cure is to find a bone marrow donor—an exceedingly rare proposition. Instead, the standard treatment for this inherited blood disorder is regular blood transfusions, with repeated hospitalizations to deal with … Continue reading One-Time, Lasting Treatment for Sickle Cell Disease May be on Horizon, According to New CIRM-Funded Study
Roadmap to our epigenome reveals the genetic switches that make one adult cell type different from others
A decade ago scientists made a huge news splash when they announced the completion of the human genome project declaring it the first road map of our genes. But it did not take long to realize that the early road map was like some of the early days of GPS systems: it lacked knowledge of … Continue reading Roadmap to our epigenome reveals the genetic switches that make one adult cell type different from others
All Things Being (Un)Equal: Scientists Discover Gene that Breaks Traditional Laws of Inheritance
One of the most fundamental laws of biology is about to be turned on its head, according to new research from scientists at the University of North Carolina (UNC) School of Medicine. As reported in the journal PLOS Genetics, UNC researchers identified a gene that does not obey traditional laws that determine how genes get … Continue reading All Things Being (Un)Equal: Scientists Discover Gene that Breaks Traditional Laws of Inheritance
‘STARS’ Help Scientists Control Genetic On/Off Switch
All life on Earth relies, ultimately, on the delicate coordination of switches. During development, these switches turn genes on—or keep them off—at precise intervals, controlling the complex processes that guide the growth of the embryo, cell by cell, as it matures from a collection of stem cells into a living, breathing organism. If you control … Continue reading ‘STARS’ Help Scientists Control Genetic On/Off Switch
Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014
2014 marked an extraordinary year for regenerative medicine and for CIRM. We welcomed a new president, several of our research programs have moved into clinical trials—and our goal of accelerating treatments for patients in need is within our grasp. As we look back we’d like to revisit The Stem Cellar’s ten most popular stories of … Continue reading Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014
Key stem cell gene controlled from afar, Canadian scientists discover
Embryonic stem cells can, by definition, mature into any cell type in the body. They are able to maintain this state of so-called pluripotency with the help of a gene called Sox2. And now, researchers at the University of Toronto (U of T) have discovered the unseen force that controls it. These findings, reported in … Continue reading Key stem cell gene controlled from afar, Canadian scientists discover
Stem cell stories that caught our eye: heart disease, blindness and replacement teeth
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Review looks at approaches to blindness. The Scientist published a nice lay level overview of various teams’ work to use stem cells to cure blindness. … Continue reading Stem cell stories that caught our eye: heart disease, blindness and replacement teeth
The Stem Cellar 