Gladstone researchers discovered a method to control the patterns stem cells form in a dish. The work was led by Senior Investigator Todd McDevitt (left) and his team, including (pictured) David Joy and Ashley Libby. When someone thinks of machine learning, the first thing that comes to mind might be the technology used by Netflix … Continue reading Machine learning used to pattern stem cells – a vital step in organ modeling
Gene editing
Good news for two CIRM-supported therapies
Jake Javier, a patient in the spinal cord injury stem cell therapy clinical trial It’s always satisfying to see two projects you have supported for a long time do well. That’s particularly true when the projects in question are targeting conditions that have no other effective therapies. This week we learned that a clinical trial … Continue reading Good news for two CIRM-supported therapies
The challenges of living with IPEX
Last week the CIRM Board awarded $5.53 million to Dr. Rosa Bacchetta at Stanford to complete the work necessary to conduct a clinical trial for IPEX syndrome. This is a rare disease caused by mutations in the FOXP3 gene which leaves people with the condition vulnerable to immune system attacks on their organs and tissues. … Continue reading The challenges of living with IPEX
Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
The governing Board of the California Institute for Regenerative Medicine (CIRM) yesterday invested $32.92 million to fund the Stem Cell Agency’s first clinical trial in Parkinson’s disease (PD), and to support three clinical trials targeting different forms of vision loss. This brings the total number of clinical trials funded by CIRM to 60. The PD … Continue reading Stem Cell Agency Approves Funding for Clinical Trials Targeting Parkinson’s Disease and Blindness
NIH collaboration aims to develop affordable gene therapies for sickle cell disease and HIV
Sickle cell disease (SCD) and HIV have a major burden on the health of impoverished communities all over the world. Of the 38 million people living with HIV all over the world, approximately 95% reside within developing countries, with 67% in sub-Saharan Africa, half of whom are living without any treatment. Fifteen million babies will … Continue reading NIH collaboration aims to develop affordable gene therapies for sickle cell disease and HIV
Time and money and advancing stem cell research
The human genome Way back in the 1990’s scientists were hard at work decoding the human genome, trying to map and understand all the genes that make up people. At the time there was a sense of hope, a feeling that once we had decoded the genome, we’d have cures for all sorts of things … Continue reading Time and money and advancing stem cell research
One family’s fight to save their son’s life, and how stem cells made it possible
CIRM's mission is very simple: to accelerate stem cell treatments to patients with unmet medical needs. Anne Klein's son, Everett, was a poster boy for that statement. Born with a fatal immune disorder Everett faced a bleak future. But Anne and husband Brian were not about to give up. The following story is one Anne … Continue reading One family’s fight to save their son’s life, and how stem cells made it possible
HIV eliminated from mice using CRISPR and LASER ART
Dr. Kamel Khalili In the United States alone, there are approximately 1.1 million people living with Human immunodeficiency virus (HIV), a virus that weakens the immune system by destroying important cells that fight off disease and infection. This number is much larger on a global scale, with 36.9 million people living with HIV as of … Continue reading HIV eliminated from mice using CRISPR and LASER ART
“A new awakening”: One patient advocate’s fight for her daughters life
We often talk about the important role that patient advocates play in helping advance research. That was demonstrated in a powerful way last week when the CIRM Board approved almost $12 million to fund a clinical trial targeting a rare childhood disorder called cystinosis. The award, to Stephanie Cherqui and her team at UC San … Continue reading “A new awakening”: One patient advocate’s fight for her daughters life
Stanford and University of Tokyo researchers crack the code for blood stem cells
Blood stem cells grown in lab Blood stem cells offer promise for a variety of immune and blood related disorders such as sickle cell disease and leukemia. Like other stem cells, blood stem cells have the ability to generate additional blood stem cells in a process called self-renewal. Additionally, they are able to generate blood … Continue reading Stanford and University of Tokyo researchers crack the code for blood stem cells
The Stem Cellar 