As an early kick off to National Sickle Cell Awareness Month – which falls in September every year – CIRM is hosting a “Ask the Stem Cell Team” FaceBook Live event tomorrow, August 28th, from noon to 1pm (PDT). The live broadcast will feature two scientists and a patient advocate who are working hard to … Continue reading Join us tomorrow at noon for “Ask the Stem Cell Team about Sickle Cell Disease”, a FaceBook Live Event
Gene editing
Stem cell therapy offers a glimpse of hope for a student battling a deadly cancer
“About a week later they gave me a call and mentioned the word ‘cancer’ to me. For a long time, I was depressed and then, I guess you accept it and try to make the most out of the time you have now.’ That is not something you expect to hear from a 24 year … Continue reading Stem cell therapy offers a glimpse of hope for a student battling a deadly cancer
CRISPR Gene Editing Tool Linked to Unexpected Collateral DNA Damage
CRISPR–Cas9 has been widely hailed as the gene editing tool of the future. But research, published in the journal Nature Biotechnology, about the effects of CRISPR/Cas9, have found it can cause unexpected genetic damage which could lead to dangerous changes in some cells. Scientists have also learned there may be some safety implications for … Continue reading CRISPR Gene Editing Tool Linked to Unexpected Collateral DNA Damage
For the first time, scientists entirely reprogram human skin cells to iPSCs using CRISPR
Back in 2012, Shinya Yamanaka was awarded the Nobel Prize in Physiology or Medicine for his group’s identification of “Yamanaka Factors,” a group of genes that are capable of turning ordinary skin cells into induced pluripotentent stem cells (iPSCs) which have the ability to become any type of cell within the body. Discovery of iPSCs … Continue reading For the first time, scientists entirely reprogram human skin cells to iPSCs using CRISPR
Gene-editing Technique in Mice Shows Promise for Genetic Disorder in Utero
For first time ever, scientists used a gene editing technique to successfully cure a genetic condition in a mouse in utero. Their findings present a promising new avenue for research into treating genetic conditions in utero.
Video: Behind the scenes of a life-saving gene therapy stem cell treatment
“We were so desperate. When we heard about this treatment were willing to do anything to come here.” In the above quote from Zahraa El Kerdi, “here” refers to UCLA, a world away from her hometown in Lebanon. In September 2015, Zahree gave birth to a son, Hussein, who appeared perfectly healthy. But by six … Continue reading Video: Behind the scenes of a life-saving gene therapy stem cell treatment
The story behind the book about the Stem Cell Agency
WHY I WROTE “CALIFORNIA CURES” By Don C. Reed It was Wednesday, June 13th, 2018, the launch day for my new book, “CALIFORNIA CURES: How the California Stem Cell Research Program is Fighting Your Incurable Disease!” As I stood in front of the audience of scientists, CIRM staff members, patient advocates, I thought to myself, … Continue reading The story behind the book about the Stem Cell Agency
SCID kid scores big on TV
One of the stories I never tire of telling is about Evie Vaccaro. She’s the little girl who was born with a fatal immune condition called severe combined immunodeficiency or SCID. Children with this condition have no immune system, no protection against infections, and often die in the first two years of life. But thanks … Continue reading SCID kid scores big on TV
Coming up with a stem cell FIX for a life-threatening blood disorder
A promising new treatment option for hemophiliacs is in the works at the Salk Institute for Biological Sciences. Patients with Hemophilia B experience uncontrolled, and sometimes life threatening, bleeding due to loss or improper function of Factor IX (FIX), a protein involved in blood clotting. There is no cure for the disease and patients rely … Continue reading Coming up with a stem cell FIX for a life-threatening blood disorder
Stem Cell Agency’s supporting role in advancing research for rare diseases
The recent agreement transferring GSK’s rare disease gene therapies to Orchard Therapeutics was good news for both companies and for the patients who are hoping this research could lead to new treatments, even cures, for some rare diseases. It was also good news for CIRM, which played a key role in helping Orchard grow to … Continue reading Stem Cell Agency’s supporting role in advancing research for rare diseases
The Stem Cellar 