CIRM-funded therapy helps “bubble babies” lead a normal life

Ja'Ceon Golden; 'cured" of SCID At CIRM we are very cautious about using the “c” word. Saying someone has been “cured” is a powerful statement but one that loses its meaning when over used or used inappropriately. However, in the case of a new study from U.C. San Francisco and St. Jude Children’s Research Hospital … Continue reading CIRM-funded therapy helps “bubble babies” lead a normal life

200 years later, the search for a cure for Parkinson’s continues

On the surface, actor Michael J. Fox, singer Neil Diamond, civil rights activist Jesse Jackson and Scottish comedian Billy Connolly would appear to have little in common. Except for one thing. They all have Parkinson’s Disease (PD). Their celebrity status has helped raise public awareness about the condition, but studies show that awareness doesn’t amount … Continue reading 200 years later, the search for a cure for Parkinson’s continues

CRISPR-Cas9 101: an overview and the role it plays in developing therapies

Illustration courtesy of TED website There has been a lot of conversation surrounding CRISPR-Cas9 in these recent months as well as many sensational news stories. Some of these stories highlight the promise this technology holds, while others emphasize a word of caution. But what exactly does this technology do and how does it work? Here … Continue reading CRISPR-Cas9 101: an overview and the role it plays in developing therapies

Promising start to CIRM-funded trial for life-threatening blood disorder

Aristotle At CIRM we are always happy to highlight success stories, particularly when they involve research we are funding. But we are also mindful of the need not to overstate a finding. To quote the Greek philosopher Aristotle (who doesn’t often make an appearance on this blog), “one swallow does not a summer make”. In … Continue reading Promising start to CIRM-funded trial for life-threatening blood disorder

Rats, research and the road to new therapies

Don Reed Don Reed has been a champion of CIRM even before there was a CIRM. He's a pioneer in pushing for funding for stem cell research and now he's working hard to raise awareness about the difference that funding is making. In a recent article on Daily Kos, Don highlighted one of the less … Continue reading Rats, research and the road to new therapies

Mending Stem Cells: The Past, Present and Future of Regenerative Medicine

To Mend: (verb used with object) to make (something broken, worn, torn or otherwise damaged) whole, sound or usable by repairing. It’s remarkable to believe, but today doctors literally have the tools to repair damaged cells. These tools are being used to treat people with diseases that were once incurable. The field of regenerative medicine has made tremendous … Continue reading Mending Stem Cells: The Past, Present and Future of Regenerative Medicine

Researcher claims to have made first gene-edited baby. But did it really happen?

Remember the Raelians? Probably not. But way back in 2002 the group, some described them as a cult, claimed it had created the world’s first cloned baby. The news made headlines all around the world raising fears we were stepping into uncharted scientific territory. Several weeks later the scientist brought in by the Raelians to … Continue reading Researcher claims to have made first gene-edited baby. But did it really happen?

Stories that caught our eye: SanBio’s Traumatic Brain Injury trial hits its target; A new approach to endometriosis; and a SCID kid celebrates Halloween in style

Hopeful signs for treating brain injuries There are more than 200,000 cases of traumatic brain injury (TBI) in the US every year. The injuries can be devastating, resulting in everything from difficult sleeping to memory loss, depression and severe disability. There is no cure. But this week the SanBio Group had some encouraging news from … Continue reading Stories that caught our eye: SanBio’s Traumatic Brain Injury trial hits its target; A new approach to endometriosis; and a SCID kid celebrates Halloween in style

Living with sickle cell disease: one person’s story of pain and prejudice and their hopes for a stem cell therapy

Whenever we hold an in-person Board meeting at CIRM we like to bring along a patient or patient advocate to address the Board. Hearing from the people they are trying to help, who are benefiting or may benefit from a therapy CIRM is funding, reminds them of the real-world implications of the decisions they make … Continue reading Living with sickle cell disease: one person’s story of pain and prejudice and their hopes for a stem cell therapy

Stem Cell Agency Invests in New Immunotherapy Approach to HIV, Plus Promising Projects Targeting Blindness and Leukemia

While we have made great progress in developing therapies that control the AIDS virus, HIV/AIDS remains a chronic condition and HIV medicines themselves can give rise to a new set of medical issues. That’s why the Board of the California Institute for Regenerative Medicine (CIRM) has awarded $3.8 million to a team from City of Hope … Continue reading Stem Cell Agency Invests in New Immunotherapy Approach to HIV, Plus Promising Projects Targeting Blindness and Leukemia