Stem Cell Roundup: Gene therapy for diabetes, alcohol is bad for your stem cells and hairy skin

The start of a new year is the perfect opportunity to turn a new leaf. I myself have embraced 2018 with open arms and decided to join my fellow millennials who live and die by the acronym YOLO. How am I doing this? Well, so far, I got a new haircut, I started doing squats … Continue reading Stem Cell Roundup: Gene therapy for diabetes, alcohol is bad for your stem cells and hairy skin

How Tom Howing turned to stem cells to battle back against a deadly cancer

As we enter the new year, CIRM’s 2017 Annual Report will be posted in less than two weeks!  Here’s one of the people we are profiling in the report, a patient who took part in a CIRM-funded clinical trial. In March of 2015, Tom Howing was diagnosed with stage 4 cancer. Over the next 18 … Continue reading How Tom Howing turned to stem cells to battle back against a deadly cancer

Harnessing the body’s immune system to tackle cancer

Often on the Stem Cellar we write about work that is in a clinical trial. But getting research to that stage takes years and years of dedicated work. Over the next few months, we are profiling some of the scientists we fund who are doing Discovery (early stage) and Translational (pre-clinical) research, to highlight the … Continue reading Harnessing the body’s immune system to tackle cancer

CHLA study explains how stem cells slow progression of kidney disorder

Not all stem cell-based therapies act by replacing diseased or damaged cells. Many treatments in clinical development rely on the injected stem cells releasing proteins which trigger the slow down or even reversal of damage caused by disease or injury. A new CIRM-funded study that’s developing a stem cell therapy for a rare kidney disease … Continue reading CHLA study explains how stem cells slow progression of kidney disorder

UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy

Last year, we wrote about a CIRM-funded team at UCLA that’s on a mission to develop a stem cell treatment for patients with Duchenne muscular dystrophy (DMD). Today, we bring you an exciting update on this research just in time for the holidays (Merry Christmas and Happy Hanukkah and Kwanza to our readers!). DMD is … Continue reading UCLA scientists on track to develop a stem cell replacement therapy for Duchenne Muscular Dystrophy

Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

Skin stem cells specialize into new skin by sensing neighborhood crowding When embarking on a road trip, the GPS technology inside our smartphones helps us know where we are and how to get where we’re going. The stem cells buried in the deepest layers of our skin don’t have a GPS and yet, they do … Continue reading Stem Cell Stories that Caught Our Eye: GPS for Skin & Different Therapies for Aging vs. Injured Muscles?

jCyte Shares Encouraging Update on Clinical Trial for Retinitis Pigmentosa

Stepping out of the darkness into light. That’s how patients are describing their experience after participating in a CIRM-funded clinical trial targeting a rare form of vision loss called retinitis pigmentosa (RP). jCyte, the company conducting the trial, announced 12 month results for its candidate stem cell-based treatment for RP. RP is a genetic disorder … Continue reading jCyte Shares Encouraging Update on Clinical Trial for Retinitis Pigmentosa

A new study suggests CRISPR gene editing therapies should be customized for each patient

You know a scientific advance is a big deal when it becomes the main premise and title of a Jennifer Lopez-produced TV drama. That’s the case for CRISPR, a revolutionary gene-editing technology that promises to yield treatments for a wide range of genetic diseases. In fact, clinical trials using the CRISPR method are already underway … Continue reading A new study suggests CRISPR gene editing therapies should be customized for each patient

Using the AIDS virus to help children battling a deadly immune disorder

More than 35 million people around the world have been killed by HIV, the virus that causes AIDS. So, it’s hard to think that the same approach the virus uses to infect cells could also be used to help children battling a deadly immune system disorder. But that’s precisely what researchers at UC San Francisco … Continue reading Using the AIDS virus to help children battling a deadly immune disorder

Scientists find switch that targets immunotherapies to solid tumors

Cancer immunotherapies harness the power of the patient’s own immune system to fight cancer. One type of immunotherapy, called adoptive T cell therapy, uses immune cells called CD8+ Killer T cells to target and destroy tumors. These T cells are made in the spleen and lymph nodes and they can migrate to different locations in … Continue reading Scientists find switch that targets immunotherapies to solid tumors