In addition to approving funding for breast cancer related brain metastases last week, the CIRM Board also approved an additional $19.7 million geared towards our translational research program. The goal of this program is to help promising projects complete the testing needed to begin talking to the US Food and Drug Administration (FDA) about holding … Continue reading CIRM Board Approves $19.7 Million in Awards for Translational Research Program
Disease Areas
CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Dr. Saul Priceman Yesterday the governing Board of the California Institute for Regenerative Medicine (CIRM) awarded $9.28 million to Dr. Saul Priceman at City of Hope to conduct a clinical trial for the treatment of breast cancer related brain metastases, which are tumors in the brain that have spread from the original site of the … Continue reading CIRM Board Approves New Clinical Trial for Breast Cancer Related Brain Metastases
Genetic defect leads to slower production of brain cells linked to one form of autism
Child with Fragile X syndrome Fragile X syndrome (FXS) is a genetic disorder that is the most common form of inherited intellectual disability in children, and has also been linked to a form of autism. Uncovering the cause of FXS could help lead to a deeper understanding of autism, what causes it and ultimately, it’s … Continue reading Genetic defect leads to slower production of brain cells linked to one form of autism
CIRM funded study identifies potential drug target for deadly heart condition
Joseph Wu is co-senior author of a study that demonstrates how patient-derived heart cells can help scientists better study the heart and screen potential therapies. Photo courtesy of Steve Fisch Heart disease continues to be the number one cause of death in the United States. An estimated 375,000 people have a genetic form of heart … Continue reading CIRM funded study identifies potential drug target for deadly heart condition
From bench to bedside: a Q&A with stem cell expert Jan Nolta
At CIRM we are privileged to work with many remarkable people who combine brilliance, compassion and commitment to their search for new therapies to help people in need. One of those who certainly fits that description is UC Davis' Jan Nolta. This week the UC Davis Newsroom posted a great interview with Jan. Rather than … Continue reading From bench to bedside: a Q&A with stem cell expert Jan Nolta
Developing a non-toxic approach to bone-crushing cancers
When cancer spreads to the bone the results can be devastating Battling cancer is always a balancing act. The methods we use – surgery, chemotherapy and radiation - can help remove the tumors but they often come at a price to the patient. In cases where the cancer has spread to the bone the treatments … Continue reading Developing a non-toxic approach to bone-crushing cancers
HIV eliminated from mice using CRISPR and LASER ART
Dr. Kamel Khalili In the United States alone, there are approximately 1.1 million people living with Human immunodeficiency virus (HIV), a virus that weakens the immune system by destroying important cells that fight off disease and infection. This number is much larger on a global scale, with 36.9 million people living with HIV as of … Continue reading HIV eliminated from mice using CRISPR and LASER ART
Breaking bad news to stem cell researchers
It’s never easy to tell someone that they are too late, that they missed the deadline. It’s particularly hard when you know that the person you are telling that to has spent years working on a project and now needs money to take it to the next level. But in science, as in life, it’s … Continue reading Breaking bad news to stem cell researchers
Stories of the week – preterm birth and mice with a human immune system
While we are here at ISSCR 2019 hearing various scientists talk about their work, we realize that there are various breakthroughs in stem cell research in a wide variety of different fields going on every day. It is wonderful to see how scientists are hard at work in developing the latest science and pushing innovation. … Continue reading Stories of the week – preterm birth and mice with a human immune system
“A new awakening”: One patient advocate’s fight for her daughters life
We often talk about the important role that patient advocates play in helping advance research. That was demonstrated in a powerful way last week when the CIRM Board approved almost $12 million to fund a clinical trial targeting a rare childhood disorder called cystinosis. The award, to Stephanie Cherqui and her team at UC San … Continue reading “A new awakening”: One patient advocate’s fight for her daughters life