The question of whether human germline modification, or the genetic modification of human reproductive cells, should be allowed or banned was discussed by a panel of experts in the Ethics, Law and Society session during Day 1 of the World Stem Cell Summit. On the panel were Aubrey de Grey, Chief Science Officer of the … Continue reading To modify, or not to modify: Experts discuss human germline modification at WSCS15
Genetic Disorders
Brain Stem Cells in a Dish to the Rescue
The best way to impress your friends at the next party you attend might be to casually mention that scientists can grow miniature brain models in a dish using human stem cells. Sure, that might scare away some people, but when you explain how these tiny brain models can be used to study many different … Continue reading Brain Stem Cells in a Dish to the Rescue
Specialized Embryonic Stem Cells Yield Insights into X Chromosome Inactivation
Please don’t be intimidated by the title of this post! By the end of this blog, you’ll be well versed in X chromosome inactivation, and you’ll understand why you should care about this topic. Males and females are different in countless ways, but the underlying cause of these differences originates with chromosomes. Women have two … Continue reading Specialized Embryonic Stem Cells Yield Insights into X Chromosome Inactivation
Stem cell stories that caught our eye: fixing defects we got from mom, lung repair and staunching chronic nerve pain
Here are some stem cell stories that caught our eye this past week. Some are groundbreaking science, others are of personal interest to us, and still others are just fun. Two ways to clean up mitochondrial defects. Every student gets it drilled into them that we get half our genes from mom and half from … Continue reading Stem cell stories that caught our eye: fixing defects we got from mom, lung repair and staunching chronic nerve pain
Stem Cell Scientists Reconstruct Disease in a Dish; Gain Insight into Deadly Form of Bone Cancer
The life of someone with Li-Fraumeni Syndrome (LFS) is not a pleasant one. A rare genetic disorder that usually runs in families, this syndrome is characterized by heightened risk of developing cancer—multiple types of cancer—at a very young age. People with LFS, as the syndrome is often called, are especially susceptible to osteosarcoma, a form … Continue reading Stem Cell Scientists Reconstruct Disease in a Dish; Gain Insight into Deadly Form of Bone Cancer
All Things Being (Un)Equal: Scientists Discover Gene that Breaks Traditional Laws of Inheritance
One of the most fundamental laws of biology is about to be turned on its head, according to new research from scientists at the University of North Carolina (UNC) School of Medicine. As reported in the journal PLOS Genetics, UNC researchers identified a gene that does not obey traditional laws that determine how genes get … Continue reading All Things Being (Un)Equal: Scientists Discover Gene that Breaks Traditional Laws of Inheritance
British Parliament votes to approve “three parent” baby law
After what is being described as “an historic debate”, the British Parliament today voted to approve the use of an IVF technique that critics say will lead to the creation of “three parent” babies. Parliament voted 382 to 128 in favor of the technique known as mitochondrial donation, which will prevent certain genetic diseases being … Continue reading British Parliament votes to approve “three parent” baby law
Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014
2014 marked an extraordinary year for regenerative medicine and for CIRM. We welcomed a new president, several of our research programs have moved into clinical trials—and our goal of accelerating treatments for patients in need is within our grasp. As we look back we’d like to revisit The Stem Cellar’s ten most popular stories of … Continue reading Stem Cell Stories that Caught Your Eye: The Most Popular Stem Cellar Stories of 2014
Speak Friend and Enter: How Cells Let the Right Travelers through their Doors
For decades, it’s been a molecular mystery that scientists were seemingly unable to solve: how do large molecules pass through the cell and into the nucleus, while others half their size remain stranded outside? But as reported in the latest issue of Nature Nanotechnology, researchers now believe they may have cracked the case. By shedding … Continue reading Speak Friend and Enter: How Cells Let the Right Travelers through their Doors
10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials
In 2004, when 59 percent of California voters approved the creation of CIRM, our state embarked on an unprecedented experiment: providing concentrated funding to a new, promising area of research. The goal: accelerate the process of getting therapies to patients, especially those with unmet medical needs. Having 10 potential treatments expected to be approved for … Continue reading 10 Years/10 Therapies: 10 Years after its Founding CIRM will have 10 Therapies Approved for Clinical Trials
The Stem Cellar 