John Cashman Cancer stem cells are one of the main reasons why cancers are able to survive surgery, chemotherapy and radiation. They are able to hide from those therapies and, at a future date, emerge and spread the cancer in the body once again. Jionglia Cheng, PhD. Jionglia Cheng, PhD., the lead author of a … Continue reading Blocking pancreatic cancer stem cells
Cancer
You can bank on CIRM
Way back in 2013, the CIRM Board invested $32 million in a project to create an iPSC Bank. The goal was simple; to collect tissue samples from people who have different diseases, turn those samples into high quality stem cell lines - the kind known as induced pluripotent stem cells (iPSC) - and create a … Continue reading You can bank on CIRM
CIRM-funded trial for blood cancer releases promising new data
A CIRM-funded trial conducted by Oncternal Therapeutics in collaboration with UC San Diego released an interim clinical data update for patients with mantle cell lymphoma (MCL), a type of blood cancer. The treatment being developed involves an antibody called cirmtuzumab (named after yours truly) being used with a cancer fighting drug called ibrutinib. The antibody … Continue reading CIRM-funded trial for blood cancer releases promising new data
New CAR-T cell therapy using scorpion venom developed to treat brain tumors
Contributed by Wikimedia Commons (Public Domain) Glioblastoma (GBM) is an aggressive form of cancer that begins in the brain and results in tumors that can be very difficult to treat. This condition has claimed the lives of Beau Biden, former Vice President Joe Biden's son, and John McCain, former Senator of Arizona. However, a new … Continue reading New CAR-T cell therapy using scorpion venom developed to treat brain tumors
Big time validation for early support
It’s not every day that a company and a concept that you helped support from the very beginning gets snapped up for $4.9 billion. But that’s what is happening with Forty Seven Inc. and their anti-cancer therapies. Gilead, another California company by the way, has announced it is buying Forty Seven Inc. for almost $5 … Continue reading Big time validation for early support
Breakthrough image could lead to better therapies
Image of a blood stem cell in its natural environment: Photo courtesy UC Merced When it comes to using stem cells for therapy you don’t just need to understand what kinds of cell to use, you also need to understand the environment that is best for them. Trying to get stem cells to grow in … Continue reading Breakthrough image could lead to better therapies
CIRM Board Meeting Highlights Important Updates to Clinical Trials
Dr. Maria T. Millan, President and CEO of CIRM, presenting the President's Report This past Thursday the governing Board of the California Institute for Regenerative Medicine (CIRM) were presented with an update on CIRM’s clinical portfolio, which to date includes 60 clinical trials in various areas including kidney failure, cancer, and other rare diseases. The … Continue reading CIRM Board Meeting Highlights Important Updates to Clinical Trials
Rave reviews for new Killer-T Cell study
Anytime you read a news headline that claims a new discovery "may treat all cancer" it's time to put your skeptic's hat on. After all, there have been so many over-hyped "discoveries" over the years that later flopped, that it would be natural to question the headline writer. And yet, this time, maybe, this one … Continue reading Rave reviews for new Killer-T Cell study
It’s official: the state of regenerative medicine is strong
A panel discussion to a packed house at the annual ARM State of the Industry briefing Calling it a “year of dramatic impact for patients” Janet Lambert, the CEO of the Alliance for Regenerative Medicine (ARM), gave the annual “State of the Industry” briefing today in San Francisco. The briefing is a traditional kick-off event … Continue reading It’s official: the state of regenerative medicine is strong
Facebook Live: Ask the Stem Cell Team
On December 12th we hosted our latest 'Facebook Live: Ask the Stem Cell Team' event. This time around we really did mean team. We had a host of our Science Officers answering questions from friends and supporters of CIRM. We got a lot of questions and didn't have enough time to address them all. So … Continue reading Facebook Live: Ask the Stem Cell Team
The Stem Cellar 